Research Study

A Phase I Study: Low-Dose Total Lymphoid Irradiation in the Treatment of Refractory Chronic Graft Versus Host Disease
Principal Investigator 
Raewyn Broady

Overview

Body Locations and Systems 
Immune System and Disorders
ClinicalTrials.gov# 
NCT02109809
Status 
Recruiting
Study Start/End 
Apr 23, 2015 to Aug 12, 2020
Locations 
Vancouver General Hospital
Name/Title 
Myra San Antonio, Research Coordinator
Phone 
604-875-4111 ext.69277
Purpose of Study 

This phase I trial studies the side effects and best dose of low-dose total lymphoid irradiation (LD-TLI) in treating patients with chronic graft-versus-host disease that has not responded to treatment with steroids. LD-TLI is a procedure in which all of the body's major lymph nodes are treated with small doses of radiation in order to reset the dysfunctional immune system. LD-TLI may work as a treatment for graft-versus-host disease caused by a bone marrow or stem cell transplant.

Eligibility 

Visit ClinicalTrials.gov for more information. 

Disclaimer 

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.