Research Study

Alzheimer's Disease (AD) and the microbiome of the gut
Principal Investigator 
Ging-Yuek Robin Hsiung


Body Locations and Systems 
Alzheimer's Disease
Study Start/End 
Dec 15, 2017 to Jun 28, 2019
UBC Hospital
Mannie Fan, Clinical Research Coordinator
Email Address
Purpose of Study 

Recent evidence suggests a connection between the gut and the brain, and that certain conditions in the gut might be associated with neurological diseases.  Research suggests that people with Alzheimer's Disease differ from healthy controls with respect to the bacteria (microbiome) present in their gut, however further research is needed.  This project aims to study whether changes in the microbiome of the gut or oral cavity can be correlated to markers and clinical measures of Alzheimer's Disease.

recruitment poster


You may be eligible to participate as a healthy control participant or an Alzheimer's Disease patient participant if:

  • you are between the ages of 50 and 85.
  • you can commit to a ~2-hour visit.
  • you are able and willing to consent to all testing procedures.
  • you are willing to provide blood, oral cheek swab, and faecal samples.
  • you have sufficient hearing, visual, and language abilities to be able to complete study procedures.

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.