Research Study

A prospective 24-month investigator sponsored trial to determine the course of cognitive function and how it relates to MRI measures and functional connectivity in healthy controls across time (Health-Cog)
Principal Investigator 
Shannon Kolind


Body Locations and Systems 
Multiple Sclerosis
Diagnosis and Therapy 
MRI Scans
Study Start/End 
Jul 1, 2018 to Jul 31, 2019
UBC Hospital
Poljanka Johnson, Research Assistant
Purpose of Study 

The purpose of this study is to collect neurocognitive data from healthy, non-MS, untreated controls to aid in the interpretation of data acquired from treatment trials using both individual neurocognitive test scores and the MS-COG composite score.  Cognitive function in healthy controls will be characterized at several time points over two years.  Neurocognitive data will be correlated with advanced and conventional MRI metrics to better understand underlying mechanisms of cognition in healthy, non-MS, untreated controls, and how this might differ from patients with MS.


Individuals aged 25-55 with no history of neurological illness may participate.


Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.