Research Study

Shoe-worn insoles for knee osteoarthritis treatment: biomechanical, imaging, and clinical outcomes
Principal Investigator 
Michael Hunt


Body Locations and Systems 
Study Start/End 
Oct 29, 2018
Centre for Hip Health and Mobility, UBC Hospital
Natasha Krowchuk. Research Coordinator
Purpose of Study 

Knee osteoarthritis is one of the most prevalent and costliest chronic health conditions affecting Canadians.  In the absence of a cure, identification of effective and inexpensive treatment strategies is paramount.  Shoe-worn insoles (orthotics) may play a role in this regard.  However, outcomes are variable, and there is a need to be able to predict those who will and will not respond to this type of treatment.  Acheiving this is the primary purpose of this study.


You may participate in this study if you:

  • are 50 years of age or older
  • have definitive medial knee osteoarthritis
  • have a history of knee pain lasting 6 months or more
  • have the ability to walk intermittently for one hour

You may not participate in this study if you:

  • are unable to speak english
  • have had knee surgery or intra-articular injection within the last 6 months
  • have current or past (within 6 weeks) oral corticosteroid use
  • have a history of knee joint replacement or tibial osteotomy
  • have any other lower limb conditions that may affect gait
  • have current or previously failed use of insoles/shoes (i.e. cessation of orthotic use due to adverse effects)

In addition, the following MRI safety criteria will be used to definitively exclude people:

  • presence of a cardiac pacemaker, wires, or defibrillator
  • presence of metal in the eye or orbit
  • presence of a ferromagnetic aneurysm clip
  • are or may be pregnant

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.