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  1. Home
  2. Our Research
  3. Mark FitzGerald

Mark FitzGerald

Professor
VCH Clinical Title(s)
Respiratory Physician
Research Focus
Lungs and BreathingAsthmaCOPD
Degrees / Designations

MB, M.Ch., BAO, MD, FRCPI,
FRCPC, FACCP, FACP

Contact Info
mark.fitzgerald@vch.ca

Biography

Dr. J. Mark FitzGerald is the co-director of the Centre for Lung Health. He previously was head of the Respiratory Medicine Divisions at both the University of British Columbia (UBC) and Vancouver General Hospital. He is past chair of the GINA Science Committee and Chair of the GINA Executive and continues to be a member of both. He is also past president of the Canadian Thoracic Society. 
 
Dr. FitzGerald graduated from University College Dublin in 1978. After interning and training in internal medicine in Dublin, he worked for two years in Lesotho as a general internist. Subsequently, he completed post-graduate training in respiratory medicine and clinical epidemiology at McMaster University before accepting a position on faculty at McMaster University in 1987. He moved to UBC in 1989 and is currently a professor of respiratory medicine at UBC.
 
Dr. FitzGerald's clinical and research interests include asthma, chronic obstructive lung disease and health outcomes. His current research focuses on health literacy and ethnicity in the management of asthma and COPD as well as the economic evaluation of asthma and its cost effective treatment. He has been involved in a number of regional and provincial initiatives to improve COPD care. As a principal investigator with the NCE AllerGen, he is involved in the evaluation of novel new asthma therapies. More recently he has been co-principal investigator on a series of studies which have demonstrated a novel new strategy for the treatment of mild asthma. He has also been extensively involved in the evaluation of novel new therapies for severe asthma. As a principal investigator with the NCE AllerGen, he is involved in the evaluation of novel new asthma therapies. He has published over 600 peer reviewed papers and editorials in high impact journals, including the New England Journal of Medicine, British Medical Journal, The Lancet, Annals of Internal Medicine and the Journal of the American Medical Association.

Research Studies

Asthma, Lungs and Breathing

Canadian Asthma Text Messaging Study

Asthma

Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma

Lungs

A Study to Evaluate the Efficacy and Safety of Dupilumab in Participants With Allergic Bronchopulmonary Aspergillosis

Nose, Lungs and Breathing

Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps

Asthma

Study to Evaluate the Effect of Benralizumab on Allergen-Induced Inflammation in Mild, Atopic Asthmatics (ARIA)

Asthma

Long-Term Safety Evaluation of Dupilumab in Patients With Asthma (LIBERTY ASTHMA TRAVERSE)

Asthma

Study of Efficacy and Safety of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment.

Asthma

Study to Evaluate Efficacy & Safety of Tralokinumab in Subjects With Asthma Inadequately Controlled on Corticosteroids (MESOS)

Asthma

Efficacy and Safety of BI 655066/ABBV-066 (Risankizumab) in Patients With Severe Persistent Asthma

COPD, Smoking

A Study to Evaluate the Safety, Efficacy and Changes in Induced Sputum and Blood Biomarkers Following Daily Repeat Doses of Inhaled GSK2269557 in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Acute Exacerbation

Eosinophilic Disorders

An Open-Label Compassionate Use and Long-Term Access Study of Mepolizumab in HES

Asthma

Evaluation of Dupilumab in Patients With Persistent Asthma

Asthma

Longitudinal Cohort Study in Participants With Severe Asthma to Assess Biomarkers

Asthma

Asthma Self-management Via Application of Telehealth (asthma)

News and Awards

Celebrating the life and distinguished career of Dr. J. Mark FitzGerald

Jan 19, 2022

Effective mild asthma management with lower steroid doses

Oct 19, 2018

Program supports COPD patients to manage condition at home

Apr 5, 2018

Ask an expert: As a healthy person, can I participate in health research focused on a specific disease or condition?

Mar 16, 2017

Poor asthma management unnecessarily drives up health care costs

Dec 2, 2016

New, effective treatment discovered for the most difficult asthma cases

Sep 7, 2016

Benralizumab injections reduce exacerbations in severe, uncontrolled asthma, according to two trials

Sep 4, 2016

Feeling asthma-free for the first time in her life

Apr 5, 2016

New director for Centre for Heart and Lung Health highlights importance of collaboration

Oct 26, 2015

Online videos in six languages help immigrant patients breathe better

Sep 4, 2014

Disputed asthma therapy has safe record in B.C.: UBC-VCH study

Nov 26, 2013

Publications

  • BMC medical research methodology -

    International severe asthma registry (ISAR): protocol for a global registry.

    FitzGerald JM, Tran TN, Alacqua M, Altraja A, Backer V, Bjermer L, Bjornsdottir U, Bourdin A, Brusselle G, Bulathsinhala L, Busby J, Canonica GW, Carter V, Chaudhry I, Cho YS, Christoff G, Cosio BG, Costello RW, Eleangovan N, Gibson PG, Heaney LG, Heffler E, Hew M, Hosseini N, Iwanaga T, Jackson DJ, Jones R, Koh MS, Le T, Lehtimäki L, Ludviksdottir D, Maitland-van der Zee AH, Menzies-Gow A, Murray RB, Papadopoulos NG, Perez-de-Llano L, Peters M, Pfeffer PE, Popov TA, Porsbjerg CM, Price CA, Rhee CK, Sadatsafavi M, Tohda Y, Wang E, Wechsler ME, Zangrilli J, Price DB
  • Lancet (London, England) -

    Triple therapy in a single inhaler: a new option for uncontrolled asthma.

    FitzGerald JM, Sadatsafavi M
  • The New England journal of medicine -

    As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.

    Bateman ED, Reddel HK, O'Byrne PM, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Siwek-Posluszna A, FitzGerald JM
  • The Lancet. Respiratory medicine -

    Improving precision in the prediction of asthma exacerbations.

    FitzGerald JM, Sadatsafavi M
  • The Lancet. Respiratory medicine -

    Predictors of enhanced response with benralizumab for patients with severe asthma: pooled analysis of the SIROCCO and CALIMA studies.

    FitzGerald JM, Bleecker ER, Menzies-Gow A, Zangrilli JG, Hirsch I, Metcalfe P, Newbold P, Goldman M
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