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  1. Home
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  3. Investigating the role of hormone therapy in depression and prostate cancer
Research Study

The Role of Androgen Deprivation Therapy In Depression in Patients with Prostate Cancer: A Longitudinal Study (RADICAL PC) – Depression Substudy

Overview

Disorders and Conditions
Cancers
Mental Health and Behaviour
Depression
Status
Recruiting
Start/End Dates
Mar 5, 2026 Nov 30, 2030
Locations
Gordon and Leslie Diamond Health Care Centre
Name/Title
Rosalie Ho, Research Operations Lead
Phone
604-875-4111 ext.62338
Email Address
rosalie.ho@vch.ca
Purpose of Study

The purpose of this study is to follow people with prostate cancer for two years to understand how often depression develops and what factors may increase the risk. Participants will complete questionnaires about their mood and well-being. By tracking these changes over time, researchers hope to better understand the relationship between prostate cancer and depression, and use this information to improve early identification and support for patients.

Eligible participants will review the study with study staff and provide consent. Participants will complete health assessments and questionnaires about mood, health and lifestyle, then will be followed for two years with yearly follow-up visits to update health information and complete questionnaires. Some study information may also be collected from medical records.

Eligibility

Men aged 45 or older with prostate cancer may be eligible if they were diagnosed within the past 12 months, started androgen deprivation therapy (ADT) within the past six months, or plan to begin ADT within the next month. Participants must be willing to provide consent. Individuals whose prostate cancer was discovered incidentally during cystectomy for bladder cancer are not eligible.

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.

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