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Recruiting

Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps

Primary Objective:

To evaluate the efficacy of dupilumab compared to placebo on a background of mometasone furoate nasal spray (MFNS) in reducing nasal congestion/obstruction (NC) severity and endoscopic nasal polyposis score (NPS) in patients with bilateral nasal polyposis (NP). In addition for Japan, reduction in computed tomography (CT) scan opacification of the sinuses will be also a co-primary objective.

Secondary Objectives:

To evaluate the efficacy of dupilumab in improving total symptoms score (TSS).

Status
Recruiting
Principal Investigator
Mark FitzGerald
Body Locations and Systems
Nose
Lungs and Breathing
Area
Vancouver
Age
18 and above
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