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  3. Diabetes Type 1

Diabetes Type 1

Recruiting

Glucose Variability in Subclinical Hypertrophy

Evaluation of insulin absorption at sites affected by clinically apparent lipohypertrophy through short-term continuous glucose monitoring has shown inconsistent results and it is yet unknown how or if subclinical lipohypertrophy affects absorption. In this study investigators propose to enroll at least 20 people who participated in phase 1 and who were determined to have subclinical lipohypertrophy to examine the correlation between glycemic control and amount of insulin injected in subclinical hypertrophic areas using capillary blood glucose and continuous glucose monitoring.

Status
Recruiting
Principal Investigator
Graydon Meneilly
Body Locations and Systems
Diabetes - Type 1
Diabetes - Type 2
Area
Vancouver
Age
19 and above

Pilot Clinical Trial of Ustekinumab in Patients With New-onset T1D (UST1D)

In type 1 diabetes (T1D), immune defense cells in the body attack and destroy insulin-producing beta cells leaving affected people with a lifelong need for daily insulin injections. Even with insulin injections, blood glucose (sugar) control is imperfect and leads to many health complications and a shortened life span. This is a pilot clinical trial to test the safety of a drug, ustekinumab, in 20 adult subjects with recent-onset T1D.

Status
Recruiting
Principal Investigator
Thomas Elliott
Body Locations and Systems
Diabetes - Type 1
Area
Vancouver
Age
18-35
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