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  3. Testing metformin to prevent oral cancer in people with oral leukoplakia or erythroplakia
Research Study

M4OC-Prevent 2.0: Phase IIb Trial of Metformin for Oral Cancer Prevention

Overview

Body Locations and Systems
Ear, Nose and Throat
Disorders and Conditions
Cancers
ClinicalTrials.gov#
NCT05237960
Status
Recruiting
Start/End Dates
Jun 1, 2023 Dec 31, 2025
Locations
Vancouver General Hospital
Name/Title
Lorna Lee, Research Manager
Phone
604-675-8057
Email Address
llee@bccrc.ca
Purpose of Study

The purpose of this study is to determine if metformin can stop changes in the mouth that are related to pre-cancer growths such as oral leukoplakia (white patches) or erythroplakia (red patches) or cancer of the mouth. The study will compare the safety and effects of metformin with the safety and effects of placebo on people’s risk of developing cancer of the mouth.

Eligibility

Visit ClinicalTrials.gov for more information.

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.

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