Research Study

The CREST-2 Registry (C2R)
Principal Investigator 
Philip A. Teal


Body Locations and Systems 
Coronary Artery Disease 
Study Start/End 
Jun 23, 2015 to Apr 30, 2019
Diamond Health Care Centre, Vancouver General Hospital
Karina Murray, Research Coordinator
604-875-4554 ext.1
Purpose of Study 

The objective of C2R is to promote the rapid initiation and completion of enrollment in the CREST-2 randomized clinical trial ( ID NCT02089217). Patients with severe symptomatic and asymptomatic carotid artery occlusive disease will be treated with carotid artery stenting (CAS) performed by experienced and skilled interventionists. Interventionists' eligibility will be determined by a multi-specialty Interventional Management Committee (IMC). Patient eligibility will include patients with standard or high-risk, symptomatic or asymptomatic carotid artery disease. Patients will be followed for the occurrence of post-procedural complications. The primary safety and quality endpoint will be the occurrence of any stroke or death within the 30-day period following the stenting procedure. The safety and quality results from C2R will guide selection of interventionists for participation in the CREST-2 randomized clinical trial. Enrollment into C2R will begin in 2015 and continue until publication of the primary results of the randomized trial.


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Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.