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  3. Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy (CREDENCE)
Research Study

A Randomized, Double-blind, Event-driven, Placebo-controlled, Multicenter Study of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Subjects With Type 2 Diabetes Mellitus and Diabetic Nephropathy

Principal Investigator
Nadia Zalunardo

Overview

Body Locations and Systems
Diabetic Kidney Problems
Diabetes - Type 2
Disorders and Conditions
Diabetes
Diabetes Complications
Diabetes Type 2
ClinicalTrials.gov#
NCT02065791
Status
Closed for Recruitment
Start/End Dates
Feb 5, 2016
Name/Title
Katy Vela, Research Assistant
Phone
604-806-9460
Email Address
kvela@providencehealth.bc.ca
Purpose of Study

The goal of this study is to assess whether canagliflozin has a renal and vascular protective effect in reducing the progression of renal impairment relative to placebo in participants with type 2 diabetes mellitus (T2DM), Stage 2 or 3 chronic kidney disease (CKD) and macroalbuminuria, who are receiving standard of care including a maximum tolerated labeled daily dose of an angiotensin-converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB).

Eligibility

Visit ClinicalTrials.gov for more information.

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.

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