Research Study

A Pilot Study to Evaluate Feasibility of Measuring Exercise's Effects on Molecular Mechanisms of Disease Progression in Newly Diagnosed Prostate Cancer Patients Undergoing Radical Prostatectomy
Principal Investigator 
Peter Black


Body Locations and Systems 
Prostate Cancer
Diagnosis and Therapy 
Surgery and Rehabilitation 
Study Start/End 
Jun 25, 2015 to Dec 31, 2018
Diamond Health Care Centre
Eugenia Wu or Olga Arsovska, Clinical Research Coordinator
604-875-4111 ext.62338
Email Address
Purpose of Study 

The investigators aim to evaluate the feasibility of a larger clinical trial assessing an exercise program during the "teachable moment" in patients with prostate cancer and measuring its effect on tumor apoptosis signaling, lipogenesis and steroidogenesis. Participants will be randomized between a 8-12 week exercise program or to standard of care only. Participants will be assessed at screening, baseline (day 0), throughout the trial intervention (days 1-84), post-intervention visit (prior to radical prostatectomy) and final study visit 6-months post-radical prostatectomy. At each assessment, physical, biological samples and psychosocial assessments will take place.


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