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  3. Investigating islet cell infusion in people with type 1 diabetes and kidney transplant
Research Study

A Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of VX-880 in Subjects With Type 1 Diabetes With a Kidney Transplant

Principal Investigator
Breay Paty

Overview

Body Locations and Systems
Endocrine System
Diagnosis and Therapy
Transplantation and Donation
Islet Cell Transplantation
Kidney Transplantation
Disorders and Conditions
Diabetes
ClinicalTrials.gov#
NCT06832410
Status
Recruiting
Start/End Dates
Mar 1, 2025 Mar 31, 2027
Locations
Vancouver General Hospital
Name/Title
Levina Ira, Research Facilitator
Phone
604-875-4111 ext.62178
Email Address
levina.ira@vch.ca
Purpose of Study

The purpose of this study is to test whether an investigational infusion of islet cells (called VX-880) would be safe, tolerable and effective in providing better control of blood sugar levels for patients with type 1 diabetes who have a kidney transplant.

Eligible participants will undergo a seven-day hospital stay at Vancouver General Hospital for the study treatment and safety monitoring tests, including physical exams, blood work, urine tests, questionnaires, COVID-19 testing and health and medication review. There will be a five-year follow up, in which participants will have outpatient appointments at Vancouver General Hospital to complete additional tests.
 

Eligibility

Visit ClinicalTrials.gov for more information.

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.

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