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  3. A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
Research Study

The EDGE Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy: Part 1

Principal Investigator
Ben Chew

Overview

Body Locations and Systems
Kidney Stones
Urinary Tract Infections
ClinicalTrials.gov#
NCT02408211
Status
Recruiting
Start/End Dates
Apr 27, 2015
Locations
UBC Hospital
Vancouver General Hospital
Name/Title
Thomas Grgic, Research Assistant
Phone
604-875-4111 ext.62421
Email Address
thomas.grgic@alumni.ubc.ca
Purpose of Study

Percutaneous nephrolithotomy (PCNL) is a surgical procedure that is standard of care for the removal of large kidney stones. PCNL involves removal of the stone(s) from the kidney through a temporary tract that is percutaneously placed through the patient's back during surgery. There is a significant risk of urinary tract infection after PCNL but wide clinical variation in use of prophylactic antibiotics in the days leading up to surgery. For patients who had already agreed to undergo PCNL, we plan to randomize them either to 1 week of preoperative antibiotic prophylaxis plus < 24 hours of perioperative IV antibiotics or to < 24 hours of perioperative IV antibiotics only. We will then compare the rates of infectious complications following PCNL for the two groups.

Eligibility

Visit ClinicalTrials.gov for more information. 

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.

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