Research Study

Stress Hormones, Mood and Women's Sexual Desire (MODEST)
Principal Investigator 
Rosemary Basson

Overview

Body Locations and Systems 
Sexual Problems in Women
ClinicalTrials.gov# 
NCT01702818
Status 
Closed to Recruitment
Study Start/End 
Jan 10, 2014 to Dec 31, 2016
Locations 
UBC Hospital
Name/Title 
Chanel Wood, Research Assistant
Phone 
604-827-1311
Email Address 
chanel.wood@vch.ca
Purpose of Study 

Women with Hypoactive sexual desire disorder (HSDD) have all measures of testosterone activity comparable to controls but lower levels of dehydroepiandrosterone (DHEA). Although DHEA is a precursor of testosterone it has other actions including involvement in the stress system. It is also linked to mood. This study focuses on measures of childhood stress, current mood and salivary and nail stress hormones, in women with and without HSDD. We hypothesize that low levels of DHEA reflect dysfunction of the neuroendocrine stress response system involving the brain, pituitary and adrenal glands where DHEA is produced.

Eligibility 

Visit ClinicalTrials.gov for more information.

Disclaimer 

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.