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  1. Home
  2. Participate in Research
  3. A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis
Research Study

A Phase III, Multicentre, Randomized, Parallel-group, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis

Principal Investigator
Anthony Traboulsee

Overview

Body Locations and Systems
Multiple Sclerosis
ClinicalTrials.gov#
NCT01194570
Status
Closed for Recruitment
Start/End Dates
Feb 1, 2012
Locations
UBC Hospital
Name/Title
Erin Gallinger, Research Coordinator
Phone
604-822-1756
Purpose of Study

This randomized, parallel group, double-blind, placebo controlled study will evaluate the efficacy and safety of ocrelizumab in participants with primary progressive multiple sclerosis. Eligible participants will be randomized 2 : 1 to receive either ocrelizumab or placebo. The blinded treatment period will be at least 120 weeks, followed by an Open Label Extension (OLE) treatment for participants in both groups who in the opinion of the investigator could benefit from further or newly initiated ocrelizumab treatment. Unless terminated early, all participants will continue their treatment with open-label ocrelizumab until the last participant who entered the OLE phase reaches 4 years of open-label ocrelizumab treatment.

Eligibility

Visit ClinicalTrials.gov for more information.

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.

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