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  3. Brett Hilton

Brett Hilton

Assistant Professor
Academic Appointment
Assistant Professor
Research Focus
Brain and NervesSpinal Cord Injury
Contact Info
hiltonlab.ca
bhilton@icord.org
604-675-8839
brett-hilton-49b0257b/

Biography

Dr. Brett Hilton is an assistant professor in the Cellular & Physiological Sciences Department at the University of British Columbia. He is also a principal investigator at the International Collaboration on Repair Discoveries and a full member of the Djavad Mowafaghian Centre for Brain Health.
 
The Hilton Lab seeks to identify the processes that prevent damaged neurons from regenerating following brain or spinal cord injury. To do this, they use a multidisciplinary strategy combining cellular, molecular, and bioinformatic approaches together with tissue clearing and 3D imaging analyses. They are also interested in identifying the cells and circuits that are most critical for mediating functional improvements after spinal cord injury, with a focus on forelimb/hand function. 

Publications

  • Nature reviews. Neuroscience -

    Neuronal maturation and axon regeneration: unfixing circuitry to enable repair.

    Hilton BJ, Griffin JM, Fawcett JW, Bradke F
  • Neuron -

    An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.

    Hilton BJ, Husch A, Schaffran B, Lin TC, Burnside ER, Dupraz S, Schelski M, Kim J, Müller JA, Schoch S, Imig C, Brose N, Bradke F
  • Neuron -

    RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury.

    Stern S, Hilton BJ, Burnside ER, Dupraz S, Handley EE, Gonyer JM, Brakebusch C, Bradke F
  • Neuron -

    Growing Myelin around Regenerated Axons after CNS Injury.

    Hilton BJ, Bradke F
  • Current biology : CB -

    RhoA Controls Axon Extension Independent of Specification in the Developing Brain.

    Dupraz S, Hilton BJ, Husch A, Santos TE, Coles CH, Stern S, Brakebusch C, Bradke F
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