Skip to main content

Main menu

  • About Us
    • Leadership
    • Our Team
    • Vision, Mission and Values
    • Health and Economic Impact
    • Research Impact Video
    • Strategic Plan
  • Our Research
    • Research Focus
      • Brain Health
      • Cancer
      • Digital Health and Artificial Intelligence
      • Heart Health
      • Healthy Aging and Mobility
      • Immune System
      • Injury and Rehabilitation
      • Lung Health
      • Mental Health and Substance Use
    • Research Centres and Programs
      • BC Centre on Substance Use
      • Centre for Aging SMART
      • Centre for Cardiovascular Innovation
      • Centre for Clinical Epidemiology and Evaluation
      • Centre for Lung Health
      • Djavad Mowafaghian Centre for Brain Health
      • Immunity and Infection Research Centre
      • International Collaboration On Repair Discoveries
      • M. H. Mohseni Institute of Urologic Sciences
      • Ovarian Cancer Research Centre
      • Community Research Program
      • Emergency Medicine Research Program
      • Hematology Research Program
      • Skin Research Program
      • Other Research Focus Areas
    • News and Stories
    • Researcher Directory
    • Events and Workshops
  • Research Services
    • New to VCHRI
      • Working at VCHRI
      • Regulations and Training
      • Membership with VCHRI
      • Learning and Development
    • Starting Your Project
      • Research Facilitation
      • Awards and Funding
      • Grant Management
      • Operational Approval
      • CST Cerner
    • Developing Your Project
      • Clinical Trials Administration
      • Clinical Research Unit
      • Research Privacy
      • Financial Policies and Procedures
    • Additional Support
      • Indigenous Health Research Unit
      • VCH-VCHRI AI Hub
      • Communications and Media Relations
      • Study Recruitment Support
      • Innovation and Industry Partnership
    • Internal Awards
    • Clinical Research
    • Indigenous Research
  • Participate in Research
    • Reasons to Participate
    • Participant Stories
    • Find a Study
    • Recruitment Support

User menu

  • Log in

Breadcrumb

  1. Home
  2. Our Research
  3. News and Stories
  4. Taking complex prostate cancer research to the next level

Taking complex prostate cancer research to the next level

Stories Nov 15, 2019 3 minutes

A new research core will help scientists tackle some of the most complex prostate cancers.

One in seven Canadian men will receive a diagnosis of prostate cancer at some point during their lifetimes. A protein bioengineering core of specialists and equipment being established at the Vancouver Prostate Centre (VPC) could open the door to new treatment avenues for men with the deadliest forms of the disease. 

“We are expanding our bench-to-bedside research pipeline,” says Vancouver Coastal Health Research Institute researcher, Dr. Nada Lallous. “We will be working with challenging cancers at the new protein bioengineering core, particularly ones that have not previously been investigated, in order to find new cancer treatments.” 

Dr. Nada Lallous is an adjunct professor with the Faculty of Medicine at the University of British Columbia (UBC), and a senior research scientist and the manager of the protein bioengineering and biophysics group at VPC.

Lallous will work in collaboration with research teams at VPC and UBC to establish the core and advance the research program.  

“Our new protein bioengineering core will increase the throughput and accuracy of our drug discovery research pipeline,” explains Lallous. “The VPC genomics group identifies important prostate cancer drivers and our experts in the computer-aided drug design group will then find molecules predicted to eliminate their function. The new core will express and purify those drivers and then validate their specificity. Molecules that show the greatest potential are then sent to UBC for structural analysis”.  

“This helps the VPC team create the most effective molecule, which could then go on to clinical trials, and eventually become treatments for patients.”

Lallous’s background prepared her for the collaboration and cross-departmental work she is doing to establish the core. Originally from Lebanon, she pursued her master’s and PhD studies in structural biochemistry and biophysics in Strasbourg, France, followed by a postdoctoral fellowship at the Spanish National Cancer Research Centre in Madrid, Spain.

Arriving at VPC in 2012, she jumped straight into research projects designed to find novel therapies for treatment-resistant prostate cancers. This work put her in touch with several different research teams at VPC and UBC, and propelled her into her current initiative: establishing the protein bioengineering core.

Protein bioengineering core could lead to greater oversight and efficiency

Tests scheduled to be completed at the new core are currently outsourced at a hefty price. Doing the same work in-house at VPC would be more cost-effective, notes Lallous, and would also give researchers more flexibility and oversight to validate and optimize their work.

“To prove that a treatment works, we often need to validate its action from multiple angles. The new core will give us more options to do that.” 

“This is really advantageous for our work, as it gives us more flexibility and greater confirmation about the potential effectiveness of a treatment before pursuing additional studies,” adds Lallous. 

The new core is being developed as part of The Accelerated Drug Discovery Using Clinical Translation research program. Many of the larger ticket items VPC needs for the core will be covered by grant money funded by a Canada Foundation for Innovation grant and a BC Knowledge Development Fund grant. However, more community support is needed to fund the best and brightest minds, and to purchase the materials necessary to run the experiments that will take place at the core. 

“Prostate cancer touches so many people,” says Lallous, who still manages to find time between her busy work schedule and raising two young children with her husband to participate in fundraisers, such as bake sales, to raise money for prostate cancer research.

“It could be my father, my brother, my husband. That is why it is so important to keep investing in research.”

You can support research at VPC through the Prost8 Lager fundraiser, which is sponsored by craft brewing companies across British Columbia. One hundred per cent of the money raised will go to the VPC.
 

Related Articles

Discovery offers new insights to understand and treat prostate cancer

Welcoming the new M. H. Mohseni Institute of Urologic Sciences to VCHRI

Prostate Centre director’s new vision for urologic sciences research

Share:

  • Facebook
  • Linkedin
  • Twitter
  • Email

Related Research Centres/Programs

Vancouver Prostate Centre

Get the latest research headlines in your inbox

Subscribe

Recent News and Stories

Type
Announcement

Celebrating the life and distinguished career of Dr. Marcel Dvorak

May 14, 2025
Type
Stories

More equitable representation needed in Parkinson’s research

May 9, 2025 parkinsons, patient engagement, women
Type
Stories

Gamified stroke recovery improves arm function

May 8, 2025 stroke, rehabilitation
See more news

Get updates!

Join our newsletter mailing list to stay up to date on features and releases.

Subscribe

Quick Links

  • News and Stories
  • Careers
  • Events
  • Media Enquiries

Follow Us

  • LinkedIn
  • X
  • YouTube

© 2025 VCHRI. All rights reserved.

  • Contact
  • Privacy Policy