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  3. Hepatitis C

Hepatitis C

Recruiting

Sofosbuvir/Velpatasvir in Adults With Chronic Hepatitis C Virus Infection Who Are on Dialysis for End Stage Renal Disease (SOF/VEL ESRD)

The primary objectives of this study are to evaluate safety, efficacy and tolerability of treatment with sofosbuvir (Sovaldi®)/velpatasvir (Epclusa®; SOF/VEL) for 12 weeks in adults with chronic hepatitis C virus (HCV) infection who are on dialysis for End Stage Renal Disease (ESRD).

Status
Recruiting
Principal Investigator
Eric Yoshida
Body Locations and Systems
Hepatitis C
Area
Vancouver
Age
18 years and above

Durability of Virologic Response and/or Viral Resistance Patterns in Participants With Chronic Hepatitis C Who Have Been Previously Treated With Grazoprevir (MK-5172) (MK-5172-017)

This three-year study (participants with chronic kidney disease [CKD] or cirrhosis will be followed for five years) multicenter study is being done to follow participants who received at least one dose of grazoprevir (MK-5172) in a previous study to determine if they remain hepatitis C virus (HCV)-RNA negative over time, and to determine if they have developed antiviral resistance. The study will also evaluate long-term adverse events in this population.

Status
Recruiting
Principal Investigator
Eric Yoshida
Body Locations and Systems
Hepatitis C
Area
Vancouver
Age
18 and above

Gilead Sustained Virologic Response (SVR) Registry

This Registry is designed to provide long term clinical and virologic follow up in subjects who have achieved sustained virologic response (SVR) while participating in a previous Gilead sponsored Hepatitis C Virus (HCV) study. This long term follow up study is observational and no treatment is provided for HCV.

Status
Recruiting
Principal Investigator
Eric Yoshida
Body Locations and Systems
Hepatitis C
Area
Vancouver
Age
18 and above

Closed for Recruitment

Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C in Canada (AMBER)

This study seeks to provide evidence of the effectiveness and obtain patient reported outcome (PRO) data for the interferon-free ABBVIE REGIMEN ± RBV in participants with chronic hepatitis C (CHC) in a real life setting across clinical practice patient populations in Canada.
 

Status
Closed for Recruitment
Principal Investigator
Eric Yoshida
Body Locations and Systems
Hepatitis C
Area
Vancouver
Age
18-99

Study of Tivantinib in Subjects With Inoperable Hepatocellular Carcinoma Who Have Been Treated With One Prior Therapy (METIV-HCC)

The purpose of this study is to determine if tivantinib (ARQ 197) is effective in treating patients with MET diagnostic-high hepatocellular carcinoma (liver cancer) who have already been treated once with another therapy.

Status
Closed for Recruitment
Principal Investigator
Alan Weiss
Body Locations and Systems
Cancer
Hepatitis C
Area
Vancouver
Age
18 and above

A Gilead Sequence Registry of Subjects Who Did Not Achieve Sustained Virologic Response

This Registry is designed to obtain long term data on participants who have failed to achieve sustained virologic response (SVR) while receiving at least one Gilead oral antiviral agent (OAV) in a previous Gilead-sponsored hepatitis C virus (HCV) study.

Status
Closed for Recruitment
Principal Investigator
Eric Yoshida
Body Locations and Systems
Hepatitis C
Area
Vancouver
Age
18 and above
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