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  3. Detecting exercise-related leg pain with a non-invasive optical method
Research Study

Early Diagnosis of Chronic Exertional Compartment Syndrome Using a Non-invasive Optical Method

Principal Investigator
Babak Shadgan

Overview

Body Locations and Systems
Hip, Leg and Foot
Pain
Status
Recruiting
Start/End Dates
Jun 1, 2025 Sep 30, 2025
Locations
ICORD – Blusson Spinal Cord Centre
Name/Title
Jocelyn Begin, Research Coordinator
Email Address
jocelyn.begin@ubc.ca
Purpose of Study

The purpose of this study is to examine the feasibility of a wireless technology named near-infrared spectroscopy (NIRS) in monitoring leg muscle blood flow and oxygenation and tissue pressure during a protocol of running. The research team will also investigate the ability of non-invasive NIRS in the diagnosis of CECS-induced leg muscle oxygen insufficiency. 

During the procedure, a small wireless NIRS sensor will be placed on the shin of both legs to monitor muscle oxygen levels. The study will begin with participants lying on their back for 10 minutes, followed by standing beside a treadmill for one minute. Participants will then walk at a moderate pace on the treadmill for 10 minutes at a 10 per cent incline. Throughout the test, participants will be asked whether they are experiencing any discomfort in the legs. After walking, participants will lie down again for a 10-minute recovery period. NIRS measurements will begin 10 minutes before exercise and will continue throughout the walking and recovery phases.

Eligibility

This study is open to healthy adults between 19 to 75 years of age with no leg pain. Participants must not be diagnosed with or suspected of having chronic exertional compartment syndrome of the lower limb. Participants must also be able to consent in English.

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.

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