Research Study

A Randomized Controlled Study of Conventional Versus Theta Burst Repetitive Transcranial Magnetic Stimulation in the Treatment of Major Depressive Disorder
Principal Investigator 
Fidel Vila-Rodriguez


Body Locations and Systems 
Diagnosis and Therapy 
MRI Scans
Disorders and Conditions 
Study Start/End 
Sep 30, 2013 to Nov 25, 2017
UBC Hospital
Chris Pang, Study Coordinator
Email Address
Purpose of Study 

This trial will compare a novel form of rTMS, intermittent Theta Burst Stimulation to the standard conventional high frequency left sided stimulation protocol. The Left dorsolateral prefrontal cortex will be the site of stimulation in both treatment conditions. The site of stimulation will be targeted using MRI co-registration. We are recruiting healthy male volunteers for a comparison group to learn about brain function differences associated with Major Depression and to characterize changes that occur with its treatment and recovery.

Recruitment poster


You are eligible to participate if:

• Do not have a history of psychiatric illnesses

• In good health

• Male, between 51-60 years of age

• Willing to undergo brain scans and psychological tests


Please note that you must not currently be using any recreational and/or non-prescription drugs or have a drinking problem. Participants will be matched to our patient group by demographics.


Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.