Parkinson's disease results from the loss of dopamine producing brain cells; however, the mechanism that start and continue this loss are still largerly unknkown. Recent research has suggested a protein called tau may contribute to the development and progression of Parksinon's disease. Using Positron Emission Tomography (PET), a brain imaging technique, we hope to determine if and how much tau is present in healthy control subjects. This control data will then be used for comparison for data collected in patients with Parkinson's and related diseases.
- We are looking for healthy men between the ages of 19 & 85 and healthy women between the ages of 30 and 85 who are interested in particpating in research using PET brain scanning. Potential candidates should not have Parkinson's disease, depression, or other memory or mood disorders, and no first degree relative with Parkinson's disease. Female candidates cannot particpate if they are pregnant or breastfeeding.
- Particpants will be invited to complete 1 PET brain scan that lasts 70 minutes, and one 5-7 minute MRI scan to help with image analysis. Brief motor, mood and cognitive assessments will aslo be completed.
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