Recruiting

Collecting data for the Pacific Parkinson’s Research Centre Biobank

The purpose of this study is to collect biospecimens (fecal, urine, blood, oral swab) and clinical data to serve as a resource for future research on Parkinson’s disease and other movement disorders. The careful collection, storage and retrieval of biospecimens and medical information for research projects are critical for improving understanding of healthy development and disease mechanisms and the subsequent development of effective treatments. Biospecimens from this biobank will be made available for ethically-approved studies.

Status
Recruiting

Utilizing machine learning to optimize Parkinson's disease treatment

The purpose of this study is to develop a means, via a wearable sensor, to detect the subtle physiological changes that may occur before wearing off (WO) of a Parkinson's disease treatment called levodopa become consciously felt to allow for medication to be taken and absorbed in time to prevent the WO from occurring.

Status
Recruiting

Coping styles and their correlation to outcomes in Parkinson's Disease

Parkinson's Disease (PD) is a progressive neurodegenerative disorder without a cure. While the search for a cure continues, there is a growing interest in psychiological approaches to manage distress in PD. The main objective of this study is to investigate various clinical outcomes in PD associated with different coping styles. Findings from this study will form the basis for projects aimed at designing interventions to foster beneficial coping styles and studies into the neural underpinnings of coping. 

Status
Recruiting

Closed for Recruitment

tDCS in Parkinson's Disease With Depression

Parkinson's disease (PD) is a progressive neurological disease that has effects on both movement and mental health. One of the most common mental health complications of PD is depression. Up to 30% of Parkinson's patients will experience depression at some point. We aim to investigate whether transcranial direct current stimulation (tDCS), a type of electrical stimulation for the brain, can improve depression in PD as well as improve motor function in PD.

Status
Closed for Recruitment

Imaging Tau Accumulation with PBB3 in Healthy Controls

Parkinson's disease results from the loss of dopamine producing brain cells; however, the mechanism that start and continue this loss are still largerly unknkown. Recent research has suggested a protein called tau may contribute to the development and progression of Parksinon's disease. Using Positron Emission Tomography (PET), a brain imaging technique, we hope to determine if and how much tau is present in healthy control subjects. This control data will then be used for comparison for data collected in patients with Parkinson's and related diseases.

Status
Closed for Recruitment
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