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  3. Immune System

Immune System

Recruiting

Inhaled Ciclesonide for Outpatients With COVID-19 (CONTAIN)

The purpose of this study is to examine the safety and efficacy of a steriod called ciclesonide in treating mild covid-19 disease. 

Status
Recruiting
Principal Investigator
Sara Belga
Body Locations and Systems
Immune System
Area
Vancouver
Age
18 and above

Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants

The purpose of this study is evaluate the safety and efficacy of a new vaccine to protect children against bacteria that can lead to pneumococcal disease. 

Status
Recruiting
Principal Investigator
Manish Sadarangani
Body Locations and Systems
Immunizations
Area
Vancouver
Age
2 months

Countermeasures for COVID-19 Pandemic

The purpose of the study is to identify immune cells and antibodies that fight the novel coronavirus (SARS-CoV-2) from individuals who have been infected and recovered from COVID-19. Neutralizing antibodies will be used for the development of new therapies and diagnostic tools for COVID-19

Status
Recruiting
Principal Investigator
Theodore Steiner
Body Locations and Systems
Immune System and Disorders
Area
Vancouver
Age
18 and above

Multiple Sclerosis, Genes, Microbes, and Medication

The purpose of the main study is to investigate adverse drug reactions from multiple sclerosis (MS) disease modifying drugs by understanding the genetic factors that contribute to their cause. 

The sub-study investigates how the MS disease modifying drugs affect microbes in the gut and how human DNA affects the changes in the gut microbes following drug treatment. We are also interested in how gut microbes might relate to progressive MS.

recruitment poster

Status
Recruiting
Principal Investigator
Helen Tremlett
Body Locations and Systems
Multiple Sclerosis
Immune System
Area
Vancouver
Age
18 and above

Closed for Recruitment

Arthritis Health Journal Proof of Concept Study (AHJ)

The purpose of this study is to determine whether an online patient passport tool called the Arthritis Health Journal can assist people with rheumatoid arthritis in managing their disease.

Status
Closed for Recruitment
Principal Investigator
Diane Lacaille
Body Locations and Systems
Rheumatoid Arthritis
Area
Vancouver
Age
18 and above

KidCove Study

The purpose of this study is to evaluate an investigational vaccine that may protect children between 6 months and 11 years old from getting sick if they come into contact with SARS-CoV-2, the virus that causes COVID-19.

Status
Closed for Recruitment
Principal Investigator
Manish Sadarangani
Body Locations and Systems
Immune System
Area
Vancouver
Age
6 months - 11 years

A Phase 1-2 Multi-Center Study Evaluating KTE-C19 in Subjects With Refractory Aggressive Non-Hodgkin Lymphoma (ZUMA-1) (ZUMA-1)

This is a single arm, open-label, multi-center, phase 1/2 study, to determine the safety and efficacy of KTE-C19, an autologous anti-CD19 chimeric antigen receptor (CAR)-positive T cell therapy, in refractory aggressive Non-Hodgkin Lymphoma (NHL).

Status
Closed for Recruitment
Principal Investigator
Kevin Song
Body Locations and Systems
Immune System and Disorders
Area
Vancouver
Age
18 and above

Determinants of late initiation and treatment interruption in a context of expansion of highly active antiretroviral therapy (HAART) in British Columbia, Canada

To identify the clinical, social and cultural determinants of late HAART initiation and to determine the impact of HIV-related care (routine access to care, physician experience, physical and social barriers to care) and use of community-based organizations on HAART uptake and retention.

Status
Closed for Recruitment
Body Locations and Systems
HIV
Area
Vancouver
Age
19 and above

Employment and Arthritis: Making it Work (MIW)

The investigators plan to conduct a randomized controlled trial to evaluate the effectiveness and the cost effectiveness of an on-line eLearning program (entitled Employment and Arthritis: Making it Work) designed to help people with inflammatory arthritis stay employed. The program also includes assessments with 1) an occupational therapist, and 2) a vocational rehabilitation counsellor at the end of the program to help participants identify and obtain necessary changes at work. People from three provinces will be recruited from collaborators' patient and program recipient lists.

Status
Closed for Recruitment
Principal Investigator
Diane Lacaille
Body Locations and Systems
Psoriatic Arthritis
Rheumatoid Arthritis
Lupus
Ankylosing Spondylitis
Area
Richmond
Age
18-59
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