Overview
Body Locations and Systems
Status
Recruiting
Purpose of Study
This study will evaluate how changes in saliva composition can affect swallowing in Sjogren’s disease and healthy individuals. Sjogren’s disease leads to changes in saliva, including the amount produced and the components in saliva (e.g. proteins). These changes can contribute to dry mouth and problems with swallowing. This research will provide information for clinicians working with swallowing disorders, to promote earlier diagnosis and treatment.
The study will involve one in-person appointment lasting approximately two hours, scheduled before noon. Participants will provide saliva samples and undergo perceptual and physiological oral and swallowing evaluations. This includes: two saliva samples collected on-site; clinical examination of the oral cavity structure and function (including dryness and food residue); measurement of tongue and lip strength and tongue endurance; completion of questionnaires regarding experiences related to dry mouth, swallowing difficulty and symptom severity; and swallowing assessment with solid food and liquid.
Eligibility
This study is open to two groups: adults who are healthy with no acute or chronic medical conditions and adults who are diagnosed with primary Sjogren’s disease.
All participants must be 19 years of age or older, fluent in spoken and written English, able to sit, walk and stand independently or with an aid (e.g. walker, cane, one-person assist), and independent with daily living activities (e.g. grooming, dressing, toileting). Healthy controls will be matched to the patient group according to demographics.
Disclaimer
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.
This study will evaluate how changes in saliva composition can affect swallowing in Sjogren’s disease and healthy individuals. Sjogren’s disease leads to changes in saliva, including the amount produced and the components in saliva (e.g. proteins). These changes can contribute to dry mouth and problems with swallowing. This research will provide information for clinicians working with swallowing disorders, to promote earlier diagnosis and treatment.
The study will involve one in-person appointment lasting approximately two hours, scheduled before noon. Participants will provide saliva samples and undergo perceptual and physiological oral and swallowing evaluations. This includes: two saliva samples collected on-site; clinical examination of the oral cavity structure and function (including dryness and food residue); measurement of tongue and lip strength and tongue endurance; completion of questionnaires regarding experiences related to dry mouth, swallowing difficulty and symptom severity; and swallowing assessment with solid food and liquid.
This study is open to two groups: adults who are healthy with no acute or chronic medical conditions and adults who are diagnosed with primary Sjogren’s disease.
All participants must be 19 years of age or older, fluent in spoken and written English, able to sit, walk and stand independently or with an aid (e.g. walker, cane, one-person assist), and independent with daily living activities (e.g. grooming, dressing, toileting). Healthy controls will be matched to the patient group according to demographics.
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.
