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  3. Bones, Joints and Muscles

Bones, Joints and Muscles

Recruiting

Reducing Fall Risk Post Hip Fracture in Mild Cognitive Impairment

The purpose of this study is to assess the efficacy of the home-based Otago Exercise Program compared with usual care in reducing fall risk among older adults with mild cognitive impairment and a fall-related hip fracture.

Status
Recruiting
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Bones, Joints and Muscles
Area
Vancouver
Age
65 and above

Implementing an evidence-based exercise program to reduce falls in older adults

The purpose of this study is to test two methods of delivering the Otago Exercise Program, which consists of strength and balance training delivered by a physiotherapist to seniors to help reduce falls and the risk of falls. 

Status
Recruiting
Principal Investigator
Linda Li
Body Locations and Systems
Bones, Joints and Muscles
Area
Vancouver
Age
65 and above

Osteoarthritis Running & Cartilage Assessment (ORCA)

The purpose of this study is to examine the safety of running for knee joint health through an assessment of running biomechanics and MRI-derived measures of cartilage composition. 

Status
Recruiting
Principal Investigator
Michael Hunt
Body Locations and Systems
Osteoarthritis
Area
Vancouver
Age
40 years and above

Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

This is a Phase 2b/3 study.  The purpose of a 2b/3 study is to learn more about the safety and effects of VX-210 in patients with acute traumatic cervical SCI.  VX-210 is an investigational drug; “in

Status
Recruiting
Principal Investigator
Brian Kwon
Body Locations and Systems
Spine
Area
Vancouver
Age
14-75 years

Decompression vs. Fusion for Stable Degenerative Spondylolisthesis

The overall purpose of this study is to assess the feasibility of a cross-country non-inferiority randomized controlled trial (RCT) comparing midline sparing decompression alone (MSDA) to usual care (decompression with fusion).

Status
Recruiting
Principal Investigator
Charles Fisher
Body Locations and Systems
Spine
Area
Vancouver
Age
50 years and above

MyndMove

Many individuals with cervical spinal cord injury (SCI) have difficulty using their hands and arms. MyndMove is a non-invasive medical device that uses short, low energy electrical pulses with surface electrodes to cause muscle contractions to produce a full range of reaching and grasping movements, which the patient is unable to perform by him/herself.

By using MyndMove therapy to help the individual move their arms and hands as he/she attempts to carry out typical reaching and grasping movements, the individual improves their ability to perform these tasks voluntarily.

Status
Recruiting
Principal Investigator
Andrea Townson
Body Locations and Systems
Spine
Area
Vancouver

Employment and Arthritis: Making it Work - Preventing work loss for people with osteoarthritis

The aim of this study is to develop an on-line eLearning self-management program to help people with osteoarthritis deal with employment issues and stay employed. 

Recruitment Poster

Status
Recruiting
Principal Investigator
Diane Lacaille
Body Locations and Systems
Osteoarthritis
Area
Vancouver
Age
18-70

SuPRA: Using Wearable Activity Trackers With a New Application to Improve Physical Activity in Knee Osteoarthritis

Physical activity is an essential first-line treatment for patients with knee osteoarthritis (OA). However, only 13% of patients meet the activity recommendation of 150 minutes or more per week. The primary goal of this randomized controlled trial is to assess the efficacy of a Fitbit Flex (a wireless physical activity tracking device) paired with a new application, plus a brief education session and telephone counselling by a physiotherapist (PT), to improve physical activity and reduce sedentary time in patients with knee osteoarthritis.

Status
Recruiting
Principal Investigator
Linda Li
Body Locations and Systems
Osteoarthritis
Area
Richmond
Age
19 and above

HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial

HIP ATTACK is an international randomized controlled trial of 1200 patients with a hip fracture that requires a surgical intervention. This trial will determine the effect of accelerated medical clearance and accelerated surgery compared to standard care on the 30-day risk of a major perioperative complication (i.e., a composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding).

Status
Recruiting
Principal Investigator
Pierre Guy
Body Locations and Systems
Hip
Area
Vancouver
Age
45 and above

Falls Prevention Clinic

At the Falls Prevention Clinic, each subject receives a comprehensive assessment of his or her individual risk factors for falling in addition to a comprehensive medical examination. Recommendations and appropriate follow up tests and referrals are ordered for patients on an individual basis.

Status
Recruiting
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Fractures
Men's and Women's Health
Area
Various sites
Age
70 and above

Reamer Irrigator Aspirator (RIA) vs Autogenous Iliac Crest Bone Graft (AICBG) for the Treatment of Non-unions

The specific question the investigators will seek to answer is: can the Reamer Irrigator Aspirator (RIA) provide a bone graft source for the treatment of nonunions that is equally effective to Autogenous Iliac Crest Bone Graft (AICBG) while resulting in a decreased amount of post-operative pain and a lower rate of complications?


 

Status
Recruiting
Principal Investigator
Pierre Guy
Body Locations and Systems
Bone Grafts
Area
Vancouver
Age
18-65

Collaborative Power Mobility Innovative Learning OpporTunity (CoPILOT) - A Pilot Study of a New Training Approach (Phase 1) (CoPILOT)

Losing the ability to walk can lead to fewer opportunities to socialize with friends and family, and participate in the community. When this happens, powered wheelchairs can provide access to homes and communities, contributing to health and well-being. Training by a qualified occupational therapist allows an individual to use a powered wheelchair safely and effectively. Learning to drive a powered wheelchair can be difficult, frustrating and time consuming for people with cognitive and physical challenges.

Status
Recruiting
Principal Investigator
Bill Miller
Body Locations and Systems
Spine
Area
Vancouver
Age
19 and above

Closed for Recruitment

Hip Health Information Project (HHIP)

The Hip Health Information Project (HHIP) is a study investigating the experiences and perceptions of pre-surgical education to prepare patients with osteoarthritis (OA) of the hip for hip replacement surgery.  The purpose of this study is to explore, through focus groups, the barriers and opportunities that exist for improving education programs for OA hip patients.

Status
Closed for Recruitment
Principal Investigator
Bill Miller
Body Locations and Systems
Osteoarthritis
Area
Various sites
Age
45 and above

Is quadricepts dysfunction common in individuals with patellofemoral pain?

To assess if thigh muscle activation is different in women with knee pain compared to those without knee pain

Status
Closed for Recruitment
Principal Investigator
Jayne Garland
Body Locations and Systems
Knee
Area
Vancouver
Age
19-35

Open Reduction Syndesmosis Tightrope Versus Screw Fixation

Tibia-fibular syndesmosis injury occurs in a significant proportion of ankle injuries and is assumed to disrupt the syndesmotic ligaments.

Status
Closed for Recruitment
Principal Investigator
Pierre Guy
Body Locations and Systems
Ankle
Area
Vancouver
Age
18 and above

Supporting Patient Care With Electronic Resource (SuPER)

This proof-of-concept randomized trial evaluates the effectiveness of using an on-line decision aid (ANSWER-2) in the decision making to start or switch biologic therapy in Canadian patients with rheumatoid arthritis.

Recruitment poster

Status
Closed for Recruitment
Principal Investigator
Linda Li
Body Locations and Systems
Rheumatoid Arthritis
Area
Various sites
Age
19 and above

OPAM-IA: Using Digital Activity Trackers to Improve Physical Activity in Inflammatory Arthritis

Being physically active can reduce pain and fatigue, improve mobility and enhance quality of life in people with arthritis, but adherence to an active lifestyle is poor, with less than half of people with arthritis being active. The primary goal of this randomized controlled trial is to assess the efficacy of a physical activity coaching model to improve physical activity participation and reduce sedentary time in patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus.

Status
Closed for Recruitment
Principal Investigator
Linda Li
Body Locations and Systems
Arthritis
Area
Vancouver
Age
19 and above

Study to Demonstrate the Efficacy (Including Inhibition of Structural Damage), Safety and Tolerability up to 2 Years of Secukinumab in Active Psoriatic Arthritis (FUTURE5)

The purpose of this study is to demonstrate efficacy including effect on inhibition of progression of structural damage, safety and tolerability up to 2 years with primary focus at Week 24, to support the use of secukinumab pre-filled syringe (PFS) by subcutaneous (s.c.) self-administration with or without loading regimen in subjects with active Psoriatic Arthritis (PsA) despite current or previous NSAID, DMARD therapy and/or previous anti-TNFα therapy.

Status
Closed for Recruitment
Principal Investigator
Jan Dutz
Body Locations and Systems
Psoriasis
Psoriatic Arthritis
Area
Vancouver
Age
18 and above

Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis (GRIP)

This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the CMC joint in the hand.

Status
Closed for Recruitment
Principal Investigator
Erin Brown
Body Locations and Systems
Osteoarthritis
Area
Various sites
Age
18 and above

MONITOR-OA: Using Wearable Activity Trackers to Improve Physical Activity in Knee Osteoarthritis

Physical activity is an essential first-line treatment for patients with knee osteoarthritis (OA). However, a 2013 systematic review found only 13% met the activity recommendation of 150 minutes or more per week. The primary goal of this randomized controlled trail is to assess the efficacy of a physical activity counseling model, involving a group education session, the use of Fitbit Flex (a wireless physical activity tracking device), and online/telephone coaching by a physiotherapist (PT), to improve physical activity and reduce sedentary time in patients with knee OA.

Status
Closed for Recruitment
Principal Investigator
Linda Li
Body Locations and Systems
Osteoarthritis
Area
Vancouver
Age
19 and above

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