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  3. Stroke

Stroke

Recruiting

PULSE (Partners Using Linked Strategies Effectively) Study

Health behaviors like physical activity and nutritious eating habits significantly reduce initial stroke risk and help prevent strokes from reoccurring. Yet, most individuals struggle to meet physical activity and nutrition recommendations. Health and health behaviors are typically linked in couples, and spouses occupy a unique position to facilitate each other’s physical activity and healthy nutrition, thereby reducing stroke risk for everyone involved. 

Status
Recruiting
Principal Investigator
Christiane Hoppmann
Body Locations and Systems
Stroke
Area
Vancouver

AMPLATZER™ LAA Occluder Post Approval Study (PAS)

The AMPLATZER LAA Occluder is a transcatheter, self-expanding nitinol device intended for use in preventing thrombus embolization from the LAA. The purpose of this study is to compile real world outcome data on the use of AMPLATZER LAA Occluder in subjects with non-valvular atrial fibrillation (NVAF)

Status
Recruiting
Principal Investigator
Jacqueline Saw
Body Locations and Systems
Atrial Fibrillation
Stroke
Area
Vancouver
Age
18 and above

A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion (TEMPO-2)

This trial will enroll patients that have been diagnosed with a transient ischemic attack (TIA) or minor stroke that has occurred within the past 12 hours. Anyone diagnosed with a minor stroke faces the possibility of long-term disability and even death, regardless of treatment. Stroke symptoms such as weakness, difficulty speaking and paralysis may improve or worsen over the hours or days immediately following a stroke. TEMPO-2 is a minor stroke trial for patients presenting within 12 hours of their symptom onset. Patients will be randomized to TNK-tPA or standard of care.

Status
Recruiting
Principal Investigator
Thalia Field
Body Locations and Systems
Stroke
Stroke
Area
Vancouver
Age
18 and above

Dabigatran Following Transient Ischemic Attack and Minor Stroke (DATAS II)

Rationale: To date, anticoagulant therapy in acute stroke has also been limited by excess hemorrhagic events. The oral anticoagulant dabigatran is a novel agent, which has been shown to be associated with much lower intracranial hemorrhage rates. It has been suggested that this agent may provide the superior benefits of anticoagulation in acute stroke, without the concomitant increase in hemorrhage risk associated with heparin/LMWH or warfarin.

Status
Recruiting
Principal Investigator
Thalia Field
Body Locations and Systems
Stroke
Area
Vancouver
Age
18 and above

Closed for Recruitment

Hyperbaric Oxygen Post Established Stroke (HOPES)

The purpose of this study is to examine the role of Hyperbaric Oxygen Therapy (HBOT) in improving neurological function in patients who are 6 to 36 months post ischemic stroke.

Status
Closed for Recruitment
Principal Investigator
David Harrison
Body Locations and Systems
Stroke
Area
Vancouver
Age
19-85

RESPECT PFO Clinical Trial

The purpose of this study is to investigate whether percutaneous Patent Foramen Ovale (PFO) closure, using the AMPLATZER PFO Occluder, is superior to current standard of care medical treatment in the prevention of recurrent embolic stroke.

Status
Closed for Recruitment
Principal Investigator
Philip A. Teal
Body Locations and Systems
Stroke
Area
Vancouver
Age
18-60
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