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Stroke

Recruiting

Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease

The purpose of the study is to better understand the safety of using combination antithrombotic therapy in patients with high risk transient ischemic attack (TIA) or ischemic stroke secondary to ICAD (intracranial atherosclerotic disease) for prevention of recurrent stroke.

Status
Recruiting
Principal Investigator
Samuel Yip
Body Locations and Systems
Stroke
Area
Vancouver
Age
40 and above

Telerehabilitation With Aims to Improve Lower Extremity Recovery Post-Stroke (TRAIL)

The purpose of the study is to examine the feasibility and effectiveness of a 4-week lower extremity telerehabilitation protocol with aims to improve lower extremity recovery amoung community-living stroke survivors. 

Status
Recruiting
Principal Investigator
Brodie Sakakibara
Body Locations and Systems
Stroke
Area
Vancouver
Age
19 and above

Characterising Arm Recovery in People With Severe Stroke (CARPSS)

The main goal of this program of research is to advance our understanding of how the severely damaged brain changes over the first 12-months post stroke. The investigators will determine 'who recovers', 'who does not recover', and 'why'

Status
Recruiting
Principal Investigator
Lara Boyd
Body Locations and Systems
Stroke
Area
Vancouver
Age
18-90

A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion (TEMPO-2)

This trial will enroll patients that have been diagnosed with a transient ischemic attack (TIA) or minor stroke that has occurred within the past 12 hours. Anyone diagnosed with a minor stroke faces the possibility of long-term disability and even death, regardless of treatment. Stroke symptoms such as weakness, difficulty speaking and paralysis may improve or worsen over the hours or days immediately following a stroke. TEMPO-2 is a minor stroke trial for patients presenting within 12 hours of their symptom onset. Patients will be randomized to TNK-tPA or standard of care.

Status
Recruiting
Principal Investigator
Thalia Field
Body Locations and Systems
Stroke
Stroke
Area
Vancouver
Age
18 and above

Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in Atrial Fibrillation (BRAIN-AF)

This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to acetylsalicylic acid in reducing stroke, transient ischemic attack (TIA) and neurocognitive decline, in subjects with non-valvular AF and with low risk of stroke.

Status
Recruiting
Principal Investigator
Anthony Fung
Body Locations and Systems
Stroke
Atrial Fibrillation
Area
Vancouver
Age
30-60

Determining Optimal Post-Stroke Exercise (DOSE)

The investigators will conduct a proof-of-concept study to provide preliminary evidence of efficacy of physical exercise dose on ambulatory function in adults undergoing sub-acute stroke rehabilitation.

Status
Recruiting
Principal Investigator
Janice Eng
Body Locations and Systems
Stroke
Area
Vancouver
Age
19 and above

Closed for Recruitment

Safety and Efficacy of NA-1 in Subjects Undergoing Endovascular Thrombectomy for Stroke (ESCAPE-NA1)

The ESCAPE-NA-1 study is designed to determine the safety and efficacy of the neuroprotectant, NA-1, in reducing global disability in subjects with major acute ischemic stroke (AIS) who are selected for endovascular revascularization.

Status
Closed for Recruitment
Principal Investigator
Thalia Field
Body Locations and Systems
Stroke
Area
Vancouver
Age
18 years and above

Reaching in Stroke

The project targets stroke survivors to investigate the effect of augmented feedback (using robotic force cues and visual feedback) on their upper limb reaching patterns and trunk compensatory movements.

Status
Closed for Recruitment
Principal Investigator
Mike Van der Loos
Body Locations and Systems
Stroke
Area
Vancouver
Age
19 and above

Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS) (NAVIGATE ESUS)

This is a study in patients who recently had a brain attack (stroke) and in whom no clear cause of the stroke could be identified. These strokes are likely due to a blood clot and therefore, can be called embolic stroke of undetermined source. The abbreviation is ESUS. The study will compare 2 blood thinners. Patients will be randomly assigned to either Rivaroxaban 15 mg or Aspirin 100 mg and the study is intended to show, if patients given rivaroxaban have fewer blood clots in the brain (stroke) or in other blood vessels.

Status
Closed for Recruitment
Principal Investigator
Thalia Field
Body Locations and Systems
Stroke
Area
Vancouver
Age
50 and above

Vitality: Promoting Cognitive Function in Older Adults With Chronic Stroke (Vitality)

The investigators will conduct a proof-of-concept randomized controlled trial study to provide preliminary evidence of efficacy of exercise training or a complex mental and social activities program for improving cognitive function in older adults with chronic stroke, compared with a stretch and relaxation program.

Recruitment Poster

Status
Closed for Recruitment
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Stroke
Area
Vancouver
Age
55 and above
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