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  3. Women's Health

Women's Health

Recruiting

Investigating endometriosis and brown adipose tissue activity

The purpose of this study is to compare brown adipose tissue (BAT) activity in women/people diagnosed with endometriosis to similar healthy controls. BAT activity is measured twice in a random order during the early part of the menstrual cycle (follicular phase) and following egg release/ovulation (luteal phase). The study team will investigate whether BAT activity in women with endometriosis differs from healthy control women who are of similar age and body mass index.

Status
Recruiting
Principal Investigator
Jerilynn C. Prior
Body Locations and Systems
Endocrine System
Endometriosis
Sexual Health
Age
19-35

Exploring strategies to identify and reduce the risk of uterine cancer

The purpose of this study is to investigate risk factors, screening tools and intervention methods that could help provide early diagnosis or prevention of uterine cancer. The study will evaluate how or if these screening and intervention methods are understood, accepted and completed by postmenopausal participants. The ultimate goal is to identify people at high risk for developing endometrial (uterine) cancer through various screening techniques and then tailor an approach to reduce risk through a program of lifestyle interventions.

Status
Recruiting
Principal Investigator
Aline Talhouk
Andrea Neilson
Body Locations and Systems
Men's and Women's Health
Menopause

Understanding perimenopausal brain health

The purpose of this study is to is to examine the effects of 12 weeks of high-intensity interval training on the cognitive health of perimenopausal women.

Status
Recruiting
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Brain and Nerves
Brain
Women's Health
Menopause
Area
Vancouver
Age
40-55

Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer (LS2)

This study will maximize identification of women with Lynch Syndrome using an enhanced screening strategy to identify those at risk. These women will be referred to genetic counselling for testing and those found to have Lynch Syndrome will be asked to invite first degree relatives to participate and undergo genetic testing for Lynch Syndrome.

Status
Recruiting
Principal Investigator
Janice Kwon
Body Locations and Systems
Ovarian Disorders
Area
Vancouver
Age
18-70

Closed for Recruitment

Exploring the health experiences of women in midlife

The purpose of this study is to examine the health experiences of women in midlife, with particular focus on menopause. The study will investigate: the impacts of menopausal symptoms on quality of life and daily living, including caregiving responsibilities and workforce participation and productivity; the health-seeking experiences and behaviours of midlife women to treat menopause symptoms; and the barriers to obtaining care to address symptoms, as well as satisfaction of care received.

Status
Closed for Recruitment
Principal Investigator
Lori Brotto
Body Locations and Systems
Women's Health
Menopause
Age
39-60

Return to Everyday Activities in the Community and Home (REACH) - 8 Week Active Living and Walking Program

The purpose of this study isto increase physical activity, reduce sitting time, and increase strength and balance in middle-aged and older adults. The REACH program will help particpants change habits and embed light acitivites througout regular daily routines.

This study takes place twice a week over 8 weeks. Particpants will be asked to complete questionaires, physical performance measures and two to three interviews.

Status
Closed for Recruitment
Principal Investigator
Maureen Ashe
Body Locations and Systems
Women's Health
Area
Vancouver
Age
55 and above

Adequacy of Vitamin B6 Status in Older Adult Women in Metro Vancouver

The goal of this study is to assess the frequency of vitamin B6 deficiency in older adult women in Metro Vancouver.

Status
Closed for Recruitment
Principal Investigator
Yvonne Lamers
Body Locations and Systems
Women's Health
Area
Vancouver
Age
51-70

Transcriptomics and Exercise in ME/CFS

To compare changes in DNA activiation before and after exercise between healthy controls and patients with ME/CFS.

Status
Closed for Recruitment
Principal Investigator
David Patrick
Body Locations and Systems
Women's Health
Area
Vancouver
Age
19 and above

The Study of Newcomer Women and Developmental Toxicants (The SEED Study)

 The purpose of this study is to investigate exposures to heavy metal exposures and other environmental chemicals among newcomer women of reproductive age (19-45 years) from India, China, Hong Kong, and Taiwan living in the Greater Vancouver area.  This study will help us determine if current levels of toxicants may be a public health concern.  The results of this study will help us to learn how to reduce future exposures. 

Status
Closed for Recruitment
Principal Investigator
Tom Kosatsky
Body Locations and Systems
Women's Health
Area
Vancouver
Age
19-45

A Physical Activity Intervention for Female Shift Workers (SWPA)

This project will assess the feasibility of a 12-week physical activity program developed specifically for females exposed to a known occupational carcinogen - shiftwork. Physical activity has been shown to decrease cancer risk, but the investigators research has found that female shift workers face unique barriers to participating in physical activity.

Status
Closed for Recruitment
Principal Investigator
Kristin Campbell
Body Locations and Systems
Women's Health
Area
Various sites
Age
under 56

QUEST: QUadrivalent Hpv vaccine Evaluation STudy

QUEST (Quadrivalent HPV Vaccine Evaluation Study) is a Canada-wide study designed to evaluate whether 2 doses of the HPV vaccine are just as effective as 3 doses at preventing Human Papillomavirus (HPV) infection and cervical cancer.

Status
Closed for Recruitment
Principal Investigator
Manish Sadarangani
Body Locations and Systems
Sexually Transmitted Diseases
Cervical Cancer
Area
Vancouver
Age
12-17

A Study of Trastuzumab Emtansine (Kadcyla) Plus Pertuzumab (Perjeta) Following Anthracyclines in Comparison With Trastuzumab (Herceptin) Plus Pertuzumab and a Taxane Following Anthracyclines as Adjuvant Therapy in Participants With Primary Breast Cancer

This two-arm, randomized, open-label, multicenter study will evaluate the efficacy and safety of Kadcyla (trastuzumab emtansine, also known as T-DM1) in combination with Perjeta (pertuzumab) versus Herceptin (trastuzumab) in combination with Perjeta and a taxane as adjuvant therapy in patients with HER2-positive primary invasive breast cancer.

Status
Closed for Recruitment
Principal Investigator
Sasha Smiljanic
Body Locations and Systems
Breast Cancer
Area
North Vancouver
Age
18 and above

Stress Hormones, Mood and Women's Sexual Desire (MODEST)

Women with Hypoactive sexual desire disorder (HSDD) have all measures of testosterone activity comparable to controls but lower levels of dehydroepiandrosterone (DHEA). Although DHEA is a precursor of testosterone it has other actions including involvement in the stress system. It is also linked to mood. This study focuses on measures of childhood stress, current mood and salivary and nail stress hormones, in women with and without HSDD.

Status
Closed for Recruitment
Principal Investigator
Rosemary Basson
Body Locations and Systems
Sexual Problems in Women
Area
Vancouver
Age
19-65

Oral Micronized Progesterone for Perimenopausal Vasomotor Symptoms

The purpose of this study is to test whether an oral micronized progesterone reduces the score, number and severity of hot flushes and night sweats in perimenopausal women. Oral micronized progesterone is molecularly identical to human progesterone, a steroid hormone. It is sold by prescription for use to prevent endometrial cancer in women taking estrogen in menopause. This research study will test whether progesterone reduces perimenopausal hot flushes and night sweats. It will also test whether progesterone improves sleep disturbances and anxiety.

Status
Closed for Recruitment
Principal Investigator
Jerilynn C. Prior
Body Locations and Systems
Menopause
Area
Vancouver
Age
35-58
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