Academic Appointment
Assistant Professor
Research Focus
Cancers

Biography

Dr. Aline Talhouk is an assistant professor in the Department of Obstetrics and Gynecology in the Faculty of Medicine at the University of British Columbia (UBC). She is principal investigator at OVCARE, where she directs a data science and informatics laboratory. 

Dr. Talhouk holds a PhD from UBC and has expertise in computational statistics and machine learning, specifically in the development and implementation of predictive models in women’s health and oncology. Her research leverages statistical computing, machine learning and artificial intelligence to translate -omics discoveries to clinical applications and bring individualized care to ovarian and endometrial cancer patients. Dr. Talhouk has also developed a nationally funded precision prevention program that uses prediction modeling to identify those at high risk for uterine cancer and direct them to risk-reducing interventions, targeted screening and surveillance. 

Dr. Talhouk is a Michael Smith Health Research BC Scholar and holds several grants from the Canadian Institutes of Health Research, the Canada Foundation for Innovation and the Canadian Cancer Society.

News and Awards

Dry lab harnesses big data for gynecologic cancer research

Oct 9, 2020

People in profile: Derek Chiu

Sep 16, 2020

Publications

  • Cancer -

    Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta-analysis.

    McAlpine JN, Chiu DS, Nout RA, Church DN, Schmidt P, Lam S, Leung S, Bellone S, Wong A, Brucker SY, Lee CH, Clarke BA, Huntsman DG, Bernardini MQ, Ngeow J, Santin AD, Goodfellow P, Levine DA, Köbel M, Kommoss S, Bosse T, Gilks CB, Talhouk A
  • Journal of translational medicine -

    From biobank and data silos into a data commons: convergence to support translational medicine.

    Asiimwe R, Lam S, Leung S, Wang S, Wan R, Tinker A, McAlpine JN, Woo MMM, Huntsman DG, Talhouk A
  • Clinical cancer research : an official journal of the American Association for Cancer Research -

    Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).

    Talhouk A, George J, Wang C, Budden T, Tan TZ, Chiu DS, Kommoss S, Leong HS, Chen S, Intermaggio MP, Gilks B, Nazeran TM, Volchek M, Elatre W, Bentley RC, Senz J, Lum A, Chow V, Sudderuddin H, Mackenzie R, Leong SCY, Liu G, Johnson D, Chen B, Group A, Alsop J, Banerjee SN, Behrens S, Bodelon C, Brand AH, Brinton L, Carney ME, Chiew YE, Cushing-Haugen KL, Cybulski C, Ennis D, Fereday S, Fortner RT, García-Donas J, Gentry-Maharaj A, Glasspool R, Goranova T, Greene CS, Haluska P, Harris HR, Hendley J, Hernandez BY, Herpel E, Jimenez-Linan M, Karpinskyj C, Kaufmann SH, Keeney GL, Kennedy CJ, Köbel M, Koziak JM, Larson MC, Lester J, Lewsley LA, Lissowska J, Lubiński J, Luk H, Macintyre G, Mahner S, McNeish IA, Menkiszak J, Nevins N, Osorio A, Oszurek O, Palacios J, Hinsley S, Pearce CL, Pike MC, Piskorz AM, Ray-Coquard I, Rhenius V, Rodriguez-Antona C, Sharma R, Sherman ME, De Silva D, Singh N, Sinn P, Slamon D, Song H, Steed H, Stronach EA, Thompson PJ, Tołoczko A, Trabert B, Traficante N, Tseng CC, Widschwendter M, Wilkens LR, Winham SJ, Winterhoff B, Beeghly-Fadiel A, Benitez J, Berchuck A, Brenton JD, Brown R, Chang-Claude J, Chenevix-Trench G, deFazio A, Fasching PA, García MJ, Gayther SA, Goodman MT, Gronwald J, Henderson MJ, Karlan BY, Kelemen LE, Menon U, Orsulic S, Pharoah PDP, Wentzensen N, Wu AH, Schildkraut JM, Rossing MA, Konecny GE, Huntsman DG, Huang RY, Goode EL, Ramus SJ, Doherty JA, Bowtell DD, Anglesio MS
  • Clinical cancer research : an official journal of the American Association for Cancer Research -

    Molecular Subtype Not Immune Response Drives Outcomes in Endometrial Carcinoma.

    Talhouk A, Derocher H, Schmidt P, Leung S, Milne K, Gilks CB, Anglesio MS, Nelson BH, McAlpine JN
  • British journal of cancer -

    A clinically applicable molecular-based classification for endometrial cancers.

    Talhouk A, McConechy MK, Leung S, Li-Chang HH, Kwon JS, Melnyk N, Yang W, Senz J, Boyd N, Karnezis AN, Huntsman DG, Gilks CB, McAlpine JN
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