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  1. Home
  2. Our Research
  3. Caigan Du

Caigan Du

VCH Clinical Title(s)
PhD
Research Focus
Kidneys and Urinary System
Contact Info
caigan@mail.ubc.ca
604-875-4111 ext 63793

Biography

Dr. Caigan Du is a scientist at the Vancouver Coastal Health Research Institute and an assistant professor in the Department of Urologic Sciences at the University of British Columbia. He received a Ph.D. degree in Biochemistry in UK and postdoctoral training in Immunology in USA. He is interested in the pathogenesis of kidney ischemia-reperfusion injury and transplant rejection, and molecular control of urinary malignancies. He has been studying the impact of kidney donor-derived factors on renal allograft rejection, and the molecular pathways of kidney injury and regeneration in experimental models. He is also interested in developing medical solution including drugs made from natural compounds for all kinds of health problems, including immune disorders, organ preservation, kidney failure and urinary cancer. He is the PI of many grant supports from the Kidney Foundation of Canada and the Canadian Institutes of Health Research.

News and Awards

Stem cell use during lung transplantation may expand organ donor pool

Jun 22, 2015

Publications

  • Surgery -

    Decrease in donor heart injury by recombinant clusterin protein in cold preservation with University of Wisconsin solution.

    Guan Q, Li S, Yip G, Gleave ME, Nguan CY, Du C
  • American journal of physiology. Renal physiology -

    Prolonged renal allograft survival by donor interleukin-6 deficiency: association with decreased alloantibodies and increased intragraft T regulatory cells.

    Wang H, Guan Q, Lan Z, Li S, Ge W, Chen H, Nguan CY, Du C
  • The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation -

    Reduction of cold ischemia-reperfusion injury by graft-expressing clusterin in heart transplantation.

    Li S, Guan Q, Chen Z, Gleave ME, Nguan CY, Du C
  • Transplantation -

    Expression of transforming growth factor-beta1 limits renal ischemia-reperfusion injury.

    Guan Q, Nguan CY, Du C
  • American journal of physiology. Renal physiology -

    Loss of clusterin expression worsens renal ischemia-reperfusion injury.

    Zhou W, Guan Q, Kwan CC, Chen H, Gleave ME, Nguan CY, Du C
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