Research Study

Establishing an Imaging Biomarker for Disease Progression in Multiple Sclerosis
Principal Investigator 
Shannon Kolind


Body Locations and Systems 
Multiple Sclerosis
Diagnosis and Therapy 
Diagnostic Imaging
Study Start/End 
Jun 1, 2017 to Jun 30, 2020
UBC Hospital
Shawna Abel, Research Assistant
Purpose of Study 

MS is a disabling neurological disease with a highly variable clinical course including acute disability (relapses when symptoms appear or worsen) and disease progression (steady accumulation of disability in the absence of relapses). There is currently no approved treatment for progressive MS. A principal pathology of MS is the destruction of myelin, which surrounds nerves to speed up signal conduction. We have developed a magnetic resonance imaging technique that provides quantitative measurements of myelin. Our aim is to establish myelin water imaging as a biomarker for disease progression, allowing efficient clinical trials to establish effective treatment options for progressive MS. 


People with clinically diagnosed multiple sclerosis as well as healthy controls.


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