The purpose of this study is to determine if there are sex differences in seatbelt fit by quantifying male and female volunteers’ seatbelt fits relative to external body geometry and skeletal posture using an upright MRI.
The purpose of the study is to compare differences in blood flow and valve pressures by two different methods in patients who are having transcatheter aortic valve replacement.
MS is a disabling neurological disease with a highly variable clinical course including acute disability (relapses when symptoms appear or worsen) and disease progression (steady accumulation of disability in the absence of relapses). There is currently no approved treatment for progressive MS. A principal pathology of MS is the destruction of myelin, which surrounds nerves to speed up signal conduction. We have developed a magnetic resonance imaging technique that provides quantitative measurements of myelin.
The Women's HARP study is a multi-center, diagnostic observational study employing standardized imaging protocols in women with MINOCA (MI with Non Obstructive Coronary Arteries) to determine the underlying diagnosis in each participant. Participants will be followed for recurrent clinical events, every 6 months, for a maximum of 3 years.
This is an observational study designed to determine the relationship between quantitative advanced MRI measures and OCT with PET measurements of microglial activation and myelin health.
The CCNA COMPASS-ND study aims to investigate the bases, commonalities, and distinguishing characteristics of Alzheimer disease and related neurodegenerative disorders.
The purpose of this study is to compare abdominal weight gain and fat distribution to changes in brain morphology in people taking antipsychotic medications.
This trial will compare a novel form of rTMS, intermittent Theta Burst Stimulation to the standard conventional high frequency left sided stimulation protocol. The Left dorsolateral prefrontal cortex will be the site of stimulation in both treatment conditions. The site of stimulation will be targeted using MRI co-registration.
Parkinson's disease results from the loss of dopamine producing brain cells; however, the mechanism that start and continue this loss are still largerly unknkown. Recent research has suggested a protein called tau may contribute to the development and progression of Parksinon's disease. Using Positron Emission Tomography (PET), a brain imaging technique, we hope to determine if and how much tau is present in healthy control subjects. This control data will then be used for comparison for data collected in patients with Parkinson's and related diseases.
Closed for Recruitment
The purpose of this study is to determine the clinical, cognitive, motor, brain imaging, genetic and biochemical biomarker characteristics of Alzheimer disease (AD), subcortical vascular disease (SVaD) and mixed dementia (AD + sVaD).