Dementia | VCH Research Institute

Recruiting

Validating markers for Alzheimer's disease

The purpose of this study is to collect brain scans, blood samples, memory test scores and cerebrospinal fluid from people with Alzheimer's disease (AD), mild cognitive impairment or no memory impairment. The information collected in the study may help characterize the early stages of AD, and shape the criteria for earlier diagnosis and treatment of AD. It will also be used to discover, standardize and validate measures and biomarkers that are used in AD research. The ADNI4 study is a continuation of the ADNI3 study and will also open to enroll new participants.

Status

Recruiting

Co-Investigation of Robotic-Assisted Virtual Care for Older People with Dementia - Phase 1

The purpose of this study is to determine ways to meet the social needs related to loneliness and isolation in seniors with dementia while examing barriers and successes surrounding the use of a robot-assisted, virtual care solution within care settings.

Status

Recruiting

Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND)

The CCNA COMPASS-ND study aims to investigate the bases, commonalities, and distinguishing characteristics of Alzheimer disease and related neurodegenerative disorders.

Recruitment Poster

Status

Recruiting

Developing a risk assessment tool for discriminating social cognition deficits in dementia from that of depression

To look at the differences in "social cognition"- the ability to look at the interpret the social world and put yourself in someone else's shoes - between people with depression, people with frontotemporal dementia and healthy controls.

Status

Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

The purpose of this study is to assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have, or are at risk of having an Alzheimer's disease-causing mutation by determining if treatment with the study drug slows the rate of progression of cognitive impairment and improves disease-related biomarkers.
This study also offers an observational component collecting cognitive assessment data until the availability of an enrolling drug treatment group, referred to as cognitive run-in (CRI).

Status

Recruiting

Closed for Recruitment

Open-Label Study of TRx0237 in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

The purpose of this study is to provide subjects who have completed participation in a Phase 2 or Phase 3 trial with TRx0237 continued access to therapy and to evaluate the long-term safety of TRx0237.

Status

Closed for Recruitment

Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS)

This study is being done to learn more about normal thinking and behavior, mild thinking and behavior problems, Frontotemporal Dementia and other forms of dementia in families in which one or more relatives have a mutation associated with Frontotemporal Dementia.

Status

Closed for Recruitment

Characterization of Dementia Due to Mixed Alzheimer and Subcortical Vascular Pathology

The purpose of this study is to determine the clinical, cognitive, motor, brain imaging, genetic and biochemical biomarker characteristics of Alzheimer disease (AD), subcortical vascular disease (SVaD) and mixed dementia (AD + sVaD).

Status

Closed for Recruitment

Subscribe to Dementia