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  1. Home
  2. Participate in Research
  3. Kidney Transplant Failure
Research Study

Effect of Immunosuppressive Medication Use on Patient Outcomes Following Kidney Transplantation Failure

Overview

Body Locations and Systems
Kidney Transplantation
Dialysis
Kidney Failure
Diagnosis and Therapy
Transplantation and Donation
Kidney Transplantation
Organ Transplantation
ClinicalTrials.gov#
nct01296061
Status
Closed for Recruitment
Start/End Dates
Mar 2, 2011
Locations
St. Paul's Hospital
Vancouver General Hospital
Name/Title
Joanne Lau, Study Coordinator
Phone
604-682-2344 ext. 64708
Purpose of Study

Primary Hypotheses:

  • Among patients who retain the failed kidney transplant, those who continue immunosuppressant medication will have more deaths than patients who discontinue these drugs
  • Among patients who retain the failed kidney transplant, those who continue immunosuppressant medication will have more hospitalizations for sepsis than patients who discontinue these drugs
  • Among patients who retain the failed kidney transplant, those who continue immunosuppressant medication will have fewer rejection events than patients who discontinue these drugs

Secondary Hypotheses:

  • Patients who undergo elective nephrectomy (to remove the failed kidney transplant) will have fewer deaths than those who retain the failed kidney transplant
  • Patients who undergo elective nephrectomy (to remove the failed kidney transplant) will have fewer hospitalizations for sepsis than those who retain the failed kidney transplant
  • Among patients who retain the failed kidney transplant, those who continue immunosuppressant medication will have lower levels of allosensitization (anti-HLA antibodies) than those who discontinue these drugs
  • Patients who undergo elective nephrectomy will have higher levels of allosensitization (anti-HLA antibodies) than patients who retain the failed kidney transplant
Eligibility

Visit ClinicalTrials.gov for more information.

Disclaimer

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician.

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