Joanne Matsubara

Professor and Director Research, Basic Sciences
Degrees / Designations 


Email Address 
604 875 4383
Mailing Address 
Dr. Joanne Matsubara Professor and Director of Research, Basic Sciences Dept Ophthalmology and Visual Sciences Eye Care Centre 2550 Willow Street Vancouver BC V5Z 3N9


Academic Appointment 
Body Locations and Systems 
Eyes and Vision
Other Areas of Research 
Alzheimer Disease
Cerebral Cortex
Drug Delivery

Dr. Joanne Matsubara received her Ph.D from University of California, San Diego and undertook fellowship training at Cold Spring Harbor Labs and at Dalhousie University. She has been at UBC since 1988 and is Professor and Director Research, Basic Sciences in the Department of Ophthalmology and Visual Sciences. She is the Assistant Director of the Centre for Macular Research. She is an Associate Member in the Department of Cellular and Physiological Sciences and is a member of the Brain Research Centre. Dr. Matsubara's research lab focuses on basic and translational research on retinal diseases including AMD, PVR, PDR and glaucoma.

Current Projects 

1. Role of amyloid beta in drusen deposits on pathogenesis of age-related macular degeneration (AMD) 2. Triggers of chronic, pro-inflammatory mediators in early stage AMD 3. Relationship of single nucleotide polymorphisms in the Complement Factor H (CFH) gene and inflammatory cytokines in choroidal vasculature and outer retina 4. Protective role of X-linked inhibitor of apoptosis (XIAP) gene regulation in AMD 5. Molecular Mechanisms underlying proliferative vitreoretinopathy (PVR) 6. Trans-scleral drug delivery for eye disease 7. Development of small molecule treatments for retinal disease. 6. Anti-inflammatory agents rescue photoreceptors in P23H rodent models of retinal degeneration