Dr. Joanne Matsubara received her Ph.D from University of California, San Diego and undertook fellowship training at Cold Spring Harbor Labs and at Dalhousie University. She has been at UBC since 1988 and is Professor and Director Research, Basic Sciences in the Department of Ophthalmology and Visual Sciences. She is the Assistant Director of the Centre for Macular Research. She is an Associate Member in the Department of Cellular and Physiological Sciences and is a member of the Brain Research Centre. Dr. Matsubara's research lab focuses on basic and translational research on retinal diseases including AMD, PVR, PDR and glaucoma.
1. Role of amyloid beta in drusen deposits on pathogenesis of age-related macular degeneration (AMD)
2. Triggers of chronic, pro-inflammatory mediators in early stage AMD
3. Relationship of single nucleotide polymorphisms in the Complement Factor H (CFH) gene and inflammatory cytokines in choroidal vasculature and outer retina
4. Protective role of X-linked inhibitor of apoptosis (XIAP) gene regulation in AMD
5. Molecular Mechanisms underlying proliferative vitreoretinopathy (PVR)
6. Trans-scleral drug delivery for eye disease
7. Development of small molecule treatments for retinal disease.
6. Anti-inflammatory agents rescue photoreceptors in P23H rodent models of retinal degeneration
- Investigative ophthalmology & visual science - 2010, Jan 19
- The American journal of pathology - 2010, Jul 7
- The American journal of pathology - 2012, Aug 20
- Investigative ophthalmology & visual science - 2008, Jan 31
- Investigative ophthalmology & visual science - 2008, Oct 30