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  3. Large Intestine

Large Intestine

Recruiting

Open-Label Extension of RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis

The purpose of the trial is to determine the safety and efficacy of RPC1063 in patients diagnosed with moderate to severe ulcerative colitis.

Status
Recruiting
Principal Investigator
Baljinder Salh
Body Locations and Systems
Ulcerative Colitis
Area
Vancouver
Age
18-75

Impact of Adalimumab on Patient-reported Outcomes in Ulcerative Colitis (UCanADA)

To evaluate the real-life effect of adalimumab on psychological distress/depression symptoms in moderate-to-severe Ulcerative Colitis (UC) patients. 

Status
Recruiting
Principal Investigator
Baljinder Salh
Body Locations and Systems
Ulcerative Colitis
Area
Vancouver
Age
18-99

Safety and Efficacy Trial of RPC1063 for Moderate to Severe Ulcerative Colitis

The purpose of this study is to determine whether RPC1063 is effective in the treatment of Ulcerative Colitis (UC).

Status
Recruiting
Principal Investigator
Baljinder Salh
Body Locations and Systems
Ulcerative Colitis
Area
Vancouver
Age
18-75

A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label.


 

Status
Recruiting
Principal Investigator
Baljinder Salh
Body Locations and Systems
Ulcerative Colitis
Area
Vancouver
Age
18-99

Closed for Recruitment

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea

This clinical study is conducted to assess the efficacy of cadazolid compared to vancomycin in subjects with Clostridium difficile-associated diarrhea (CDAD).

Status
Closed for Recruitment
Principal Investigator
Theodore Steiner
Body Locations and Systems
Clostridium Difficile Infections
Area
Vancouver
Age
18 and above

A Prospective Trial of Frozen-and-Thawed Fecal Microbiota Transplantation for Recurrent Clostridium Difficile Infection

The primary goal of this proposal is to study the outcome of patients with recurrent Clostridium Difficile Infection (CDI) treated with frozen Fecal Microbiota Transplantation (FMT) in an open-labelled controlled trial.

Status
Closed for Recruitment
Principal Investigator
Theodore Steiner
Body Locations and Systems
Clostridium Difficile Infections
Area
Vancouver
Age
18 and above

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD2)

This is the first prospective, multi-center, double-blinded, randomized controlled study of a microbiota suspension derived from intestinal microbes. Patients who have had at least two recurrences of C. difficile infection (CDI) after a primary episode and have completed at least two rounds of standard-of-care oral antibiotic therapy or have had at least two episodes of severe CDI resulting in hospitalization may be eligible for the study.

Status
Closed for Recruitment
Principal Investigator
Theodore Steiner
Body Locations and Systems
Clostridium Difficile Infections
Area
Vancouver
Age
18 and above

Study of a Candidate Clostridium Difficile Toxoid Vaccine (Cdiffense) in Subjects at Risk for C. Difficile Infection

The aim of this study is to evaluate the efficacy of the candidate Clostridium difficile (C. difficile) vaccine to prevent primary symptomatic C. difficile infection (CDI) in subjects a risk for CDI where there is a substantial unmet medical need.

Status
Closed for Recruitment
Principal Investigator
Theodore Steiner
Body Locations and Systems
Clostridium Difficile Infections
Area
Vancouver
Age
50 and above
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