Research Study

Brain Health: Effects of Exercise on Hippocampal Volume and Memory Deficits in Persons With Schizophrenia
Principal Investigator 
Donna Jane M Lang


Body Locations and Systems 
Disorders and Conditions 
Study Start/End 
Mar 15, 2017 to Dec 31, 2018
UBC Hospital, Vancouver General Hospital
Melissa Woodward, PhD Student
604-875-2000 ext.4731
Email Address
Purpose of Study 

To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers. Psychosis patients often suffer from a number of cognitive difficulties, including poor memory function, poor problem-solving capacity and difficulties with attention and concentration. These problems are not well addressed by current clinical treatments. Evidence from aging research strongly suggests that increased cardiovascular fitness may provide numerous cognitive benefits by promoting brain growth, particularly in the frontal lobes and the hippocampi. The current study will measure the effects of aerobic exercise on brain volumes in a population of chronic psychosis patients to determine if 1) hippocampal volumes increase in response to exercise and 2) if parallel improvements in cognitive functioning occur.


Visit for more information.


Please note that this study is currently recruiting healthy volunteers who have not participated in any post-secondary education only. 


Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers and email addresses are provided for obtaining additional information on specific research studies only. If you have specific questions which require clinical expertise, please call your primary care physician.