The purpose of this study is to evaluate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) to treat depression.
The purpose of this study is to test the feasibility of Magnetic Seizure Therapy for treating depression in patients diagnosed with Parkinson's Disease.
The bWell Cognitive Care Platform to improve workplace functioning: Individuals with lived experience user interviews
The purpose of this study is to gather qualitative data from patients with depression who report functional deficits that interfere with their employment.
The purpose of this study is to examine the efficacy of the drug Cariprazine (VRAYLAR®) in improving cognition in patients with bipolar disorder.
A virtual reality intervention to improve workplace functioning in depression: Health professional end user interviews
The purpose of this study is gather qualitative data from clinicians and care providers to assess the feasibility and efficacy of implementing a novel cognitive remediation program for treating treating cognitive deficits related to depression through the usage of immersive virtual reality.
The purpose of this study is to evaluate the use of an oral multi-strain probiotic in the treatment of anxiety in individuals with Parkinson's Disease.
The purpose of this study is to assess the effects of the COVID-19 outbreak and related quarantine measures on the physical and mental well-being of health care workers, as well as the general population.
The purpose of this study is to learn about biomarkers (biological features such as proteins, genes, and brain images that indicate the state of a disease in a person), and how they can help predict treatment outcomes in patients with clinical depression.
The purpose of this study is to establish a local registry comprised of patients with Parkinson's Disease and Parkinson Plus Syndromes to mainstream research efforts and find more efficient ways to treat Parkinson's Disease.
This study is exploring certain aspects of the blood and brain to determine how a person may recover from COVID-19. In addition, this study will examine how the different aspects of COVID-19 may affect how a person thinks or feels.
tDCS (transcranial Direct Current Stimulation) is a brain stimulation technique that involves passing a very low current through the scalp to change the excitability of underlying brain regions. Moreover, yoga and meditation have recently gained popularity for their proposed health benefits. This study seeks to investigate whether there is a combined effect of yoga, meditation, and tDCS on cognition.
The goal of the current study is to determine the prevalence, rate, and types of pregnancy complications and early life events that may be associated with the emergence of psychosis and related metabolic disorder in patients with schizophrenia spectrum disorders.
To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers. Psychosis patients often suffer from a number of cognitive difficulties, including poor memory function, poor problem-solving capacity and difficulties with attention and concentration. These problems are not well addressed by current clinical treatments.
The Wellness Monitoring for Major Depressive Disorder (MDD) study is a prospective, longitudinal, observational study aimed at identifying biomarkers of relapse in MDD. Results may help refine clinical approach to relapse management, and may ultimately help MDD patients sustain wellness while on antidepressant medication.
This is a randomized, double-blind, placebo-controlled, multicentre, parallel-group study to assess the cognitive effects of lurasidone in bipolar I and II patients (manic depression) who are in remission from an episode. Participants who show cognitive impairment at the screening visit will be enrolled into the study and randomized at the baseline visit to receive either lurasidone or placebo adjunctive therapy in a 1:1 ratio for 6 weeks.
Current Canadian Clinical Practice guidelines emphasize the need for effective psychosocial adjuncts to pharmacotherapy for schizophrenia (Canadian Psychiatric Association 2005). This randomized control trial seeks to contribute to the body of evidence supporting psychosocial treatments by assessing the effectiveness of metacognitive training (MCT) and cognitive remediation (CR) at treating the persistent positive and cognitive symptoms of schizophrenia.
Developing a risk assessment tool for discriminating social cognition deficits in dementia from that of depression
To look at the differences in "social cognition"- the ability to look at the interpret the social world and put yourself in someone else's shoes - between people with depression, people with frontotemporal dementia and healthy controls.
This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or inattentive-type (ADHD-IA) and currently on > 20 mg/day of psychostimulants (psychostimulants) on: a) their current dose of psychostimulants, vs. b) a lower-dose of psychostimulants (half of their current dose).
The perception of music requires coordinated neural activities in distributed multi-functional centers across both hemispheres. The association between musical abilities and other general cognitive functions have been studied in several populations with inconsistent results.
Parkinson's disease (PD) is a progressive neurological disease that has effects on both movement and mental health. One of the most common mental health complications of PD is depression. Up to 30% of Parkinson's patients will experience depression at some point. We aim to investigate whether transcranial direct current stimulation (tDCS), a type of electrical stimulation for the brain, can improve depression in PD as well as improve motor function in PD.