B.Sc. Hon, Ph.D.
Dr. Dirk Lange is a microbiologist who earned his Ph.D. in Microbiology and Immunology from the University of Western Ontario (London, Ontario) on understanding the role of the capsular polysaccharide in the pathogenesis of Campylobacter jejuni.
Dr. Lange completed his post-doctoral fellowship at The Stone Centre at VGH with Dr. Ben Chew, where he contributed significantly to the area of urinary biomaterial design, providing a basic science perspective to understanding ureteral stent related morbidity.
Due to his significant contributions to the research program at the Stone Centre, Dr. Lange was recruited to the Department of Urologic Sciences as an Assistant Professor in 2011, and is also the Director of Basic Science Research at the Stone Centre.
His current research interests are in the area of ureteral stent associated morbidity, with specific emphasis on biomaterial design and the development of mechanisms that prevent bacterial adhesion, colonization and biofilm formation on the surface of ureteral stents and urinary catheters. In addition to this, he is currently working to improve the understanding of molecular mechanisms that regulate ureteral peristalsis in the presence of ureteral stents as well as ureteral obstruction.
In addition to this, Dr. Lange is involved in collaborative work with Dr. Alan So (Urology, UBC) and Dr. John Smit (Microbiology, UBC) aimed at studying the use of non-pathogenic bacteria in the treatment of superficial bladder cancer.
To date Dr. Lange’s contributions to Endourology and particularly Stone Disease have been recognized by the Endourological Society with the “Best Endourology Paper” award at the World Congress of Endourology in 2009, the “Best Research Presentation” at the World Congress of Endourology in 2010 and the “Most Innovative Paper” at the World Congress of Endourology in 2011. He has been invited to speak at international stent symposiums on his work regarding biofilms and ureteral stents. In addition Dr. Lange has been recognized as a Vancouver Coastal Health Research Institute Rising Star for his contributions to research and mentorship of students and colleagues. Most recently, he was awarded the Joseph Segura Scholarship in Endourology and Stone Management by the Endourological Society and the Urologic Care Foundation (American Urological Association).
- The Journal of urology - 2013, Jan 14
- Biomaterials - 2011, Mar 28
- The Journal of urology - 2009, Aug 13
- Nature reviews. Urology - 2009, Aug 6
- Journal of endourology / Endourological Society - 2011, Jun 14