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Cancer driver discovery opens up treatment pathways for rare pediatric disease

Submitted by vivian.sum@vch.ca on September 25, 2023 - 10:51am

Vancouver Coastal Health Research Institute (VCHRI) researchers Drs. Yemin Wang and David Huntsman have unlocked new research pathways into the development of rare cancers in DICER1 syndrome patients that are mainly infants and toddlers. Triggered by non-classical, two-hit mutations in the DICER1 gene responsible for the management of the production of many other genes, DICER1 tumours can progress quickly and become deadly.  

“Our findings are the first to validate the driver of the disease,” states Huntsman. 

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3 minutes

Sniffing sleuths: Canine disease detectives

Submitted by vivian.sum@vch.ca on September 9, 2023 - 8:00am

Dogs who can sniff out disease could be a valuable addition to certain clinical settings, according to research led by Vancouver Coastal Health Research Institute researchers Dr. Marthe Charles and Dr. Elizabeth Bryce.

For their pilot study, published in the Journal of the Association of Medical Microbiology and Infectious Disease Canada, the research team recruited specialist dogs and their trainers for an experiment to see whether the dogs could detect COVID-19 by its smell.

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3 minutes

Introducing the 2023/24 VCHRI Trainee Committee

Submitted by vivian.sum@vch.ca on September 7, 2023 - 12:13pm

Nestled within the Vancouver Coastal Health Research Institute (VCHRI), a vibrant community of emerging scientists is propelling scientific advancements in British Columbia and beyond. The VCHRI Trainee Committee emerges as a pivotal platform to support the growth of future health researchers. 

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5 minutes

Community care for complex health needs

Submitted by vivian.sum@vch.ca on September 5, 2023 - 12:57pm

Opportunities to connect with the broader community are not always available to the over 7,000 British Columbians living with HIV and other complex care needs, such as mental illness and substance use. Faced with stigma and marginalisation, these individuals often find themselves pushed to the edges of society.

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4 minutes

CTMS SOPs

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VCHRI has developed a set of institutional Standard Operating Procedures (SOPs) for the provincial Clinical Trial Management System (CTMS), a program administered by the BC Academic Health Science Network.

Lessons from the transition to virtual care

Submitted by vivian.sum@vch.ca on August 17, 2023 - 12:21pm

The COVID-19 pandemic brought about unprecedented change in the day-to-day practices of many physicians. Transitioning to virtual care impacted how physicians felt about many aspects of their roles and increased stress, according to the results of a study led by Vancouver Coastal Health Research Institute researcher Dr. Kevin Eva and Island Health internal medicine clinician and researcher Dr. Valeria Stoynova.

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3 minutes

First-of-its-kind genetic-matching for precision organ transplantation

Submitted by vivian.sum@vch.ca on August 11, 2023 - 12:12pm

Advanced genetic matching technology could result in significantly lower rates of organ transplant rejection, according to ongoing award-winning research led by Vancouver Coastal Health Research Institute researcher Dr. Paul Keown.

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3 minutes

Evaluating the safety of an immunotherapy drug for acute lymphoblastic leukemia

A Study of Subcutaneous Blinatumomab Administration in Acute Lymphoblastic Leukemia (ALL) Patients
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Personalized support could lead to better management of type 2 diabetes

Submitted by vivian.sum@vch.ca on August 4, 2023 - 12:33pm

Peer support has promising results for people living with type 2 diabetes, according to the findings of a recent Vancouver Coastal Health Research Institute (VCHRI)-led study, published in Diabetic Medicine.

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4 minutes

Transforming cervical cancer care

Submitted by vivian.sum@vch.ca on August 1, 2023 - 11:54am

A simple hysterectomy has been found to be a viable, effective alternative to a more invasive procedure for women with low-risk, early-stage cervical cancer. The results of the SHAPE (Simple Hysterectomy And PElvic lymphadenectomy) study co-led by Vancouver Coastal Health Research Institute researchers Dr. Janice Kwon and Dr. Lori Brotto show that patients who received the less invasive procedure experienced the same clinical outcomes as those who received a radical hysterectomy. 

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3 minutes

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