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  3. Christopher West

Christopher West

Associate Professor
Academic Appointment
Associate Professor
Research Focus
Blood, Heart and CirculationBrain and Nerves Rehabilitation Intervention
Degrees / Designations

B.Sc., M.Sc., PhD

Contact Info
chris.west@ubc.ca
DrCRWest

Biography

Dr. Christopher West directs the Translational Integrative Physiology Laboratory, which has two main aims. The first is to understand the pathways that control cardiorespiratory and autonomic function after spinal cord injury and how to effectively manipulate them to improve the function of these systems. To achieve this first aim, Dr. West’s laboratory takes a translational approach to their research by conducting studies in a variety of animal models as well as individuals and athletes with spinal cord injury. The second main aim is to conduct fundamental research related to better understanding the cardiac inotropic response to reflexive activation of the cardiovascular centres in the brainstem. To achieve this second aim, Dr. West’s laboratory utilizes a range of experimental approaches in small and large animal models, including bilateral cardiac catheterization, high-resolution imaging and direct neural recordings. Major recent findings in the lab have demonstrated that the heart is a more appropriate target than the vasculature to optimize spinal cord perfusion in the acute setting post-injury.

News and Awards

People in profile: Ryan Hoiland

Nov 16, 2021

People in profile: Brian Hayes

Sep 20, 2018

Publications

  • American journal of physiology. Heart and circulatory physiology -

    Experimental high thoracic spinal cord injury impairs the cardiac and cerebrovascular response to orthostatic challenge in rats.

    Hayes BD, Fossey MPM, Poormasjedi-Meibod MS, Erskine E, Soriano JE, Scott B, Rosentreter R, Granville DJ, Phillips AA, West CR
  • Respiratory physiology & neurobiology -

    How does cervical spinal cord injury impact the cardiopulmonary response to exercise?

    Gee CM, Eves ND, Sheel AW, West CR
  • Neurorehabilitation and neural repair -

    Effects of a Tailored Physical Activity Intervention on Cardiovascular Structure and Function in Individuals With Spinal Cord Injury.

    Williams AM, Ma JK, Martin Ginis KA, West CR
  • Nature communications -

    Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury.

    Williams AM, Manouchehri N, Erskine E, Tauh K, So K, Shortt K, Webster M, Fisk S, Billingsley A, Munro A, Tigchelaar S, Streijger F, Kim KT, Kwon BK, West CR
  • The Journal of physiology -

    A porcine model for studying the cardiovascular consequences of high-thoracic spinal cord injury.

    West CR, Poormasjedi-Meibod MS, Manouchehri N, Williams AM, Erskine EL, Webster M, Fisk S, Morrison C, Short K, So K, Cheung A, Streijger F, Kwon BK
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