Following promising study results on the effectiveness of bendamustine and rituximab (BR) for treating mantle cell lymphoma in a clinical trial setting, researchers have now discovered that the combined treatment has similar effectiveness in a general patient population.
Bendamustine is a type of chemotherapy medication that kills fast-growing cells in the body, such as cancer cells. And rituximab is an antibody therapy that works to deplete B-cells.
Sleep apnea can be a pain in the neck for sufferers and their significant others. It can also increase the risk of developing other harmful health conditions. A new National Institutes of Health-funded study is delving deeper into individuals’ biological traits using state-of-the-art genetic and epigenetic sequencing, along with other approaches, in an effort to improve and extend the lives of people with obstructive sleep apnea (OSA).
A greater understanding of how COVID-19 affects people individually has researchers calling for a more targeted and cross-disciplinary approach to medical research and patient care.
“There can be a tendency in the health care field to operate in silos,” says Dr. Mypinder Sekhon, a Vancouver Coastal Health Research Institute (VCHRI) scientist and the lead author of a editorial on the COVID-19 cytokine storm syndrome (CSS) controversy that was published in the European Respiratory Journal.
Older Canadians tend to spend more time sitting than any other age group, which can impact both their physical and mental health. Despite this, researchers have discovered that seniors who are more physically active were less likely to have the characteristic thinning of the cerebral cortex that often goes hand-in-hand with cognitive decline.
A small molecule that packs a big anti-inflammation activation punch may provide relief to the millions of individuals around the world who suffer from ulcerative colitis and other inflammation-related diseases, according to the findings of a new study published in iScience.
When the human body is sensing its movement, location and positioning, also known as proprioception, many neural systems are hard at work. Researcher Dr. Robyn Mildren has a keen appreciation for these systems and how their changes due to aging can lead to mobility issues and falls, particularly for older adults.
When Dr. Vinay Dhingra first read a study, which seemed to prove the benefits of vitamin C for treating septic shock, he was skeptical.
“The study was quite small, and the benefit quite high considering,” recalls the Vancouver Coastal Health Research Institute clinician-scientist who has worked in the Intensive Care Unit (ICU) at Vancouver General Hospital since 1998.
Every year, more than 20,000 Canadians suffer a traumatic brain injury (TBI) that requires hospitalization1. Although TBI is common because of everyday events like playing sports, car crashes, and falls, how to best treat TBI remains a challenge, says Vancouver Coastal Health Research Institute scientist Dr. John Tallon.
This is a general introduction to the important role statistics play in the planning stage of a research project. We will discuss the best practices for carrying out the crucial steps in the research process: specifying the scientific question, defining the study population, designing a study to collect and analyse the data, making appropriate conclusions based on the analysis results.
