Substance Use

The purpose of this study is to use a driving simulator to investigate how cannabis impacts driving performance in supervised medical cannabis patients who take cannabis for pain, sleep disorders, anxiety or depression.

The study involves driving on a simulator, completing cognitive tasks and providing breathalyzer, urine and blood samples. In some sessions, participants may be asked to consume their regular prescribed daytime dose of cannabis (orally or inhaled).

The purpose of this study is to examine spontaneous (i.e., not cued or externally triggered) craving in cigarette smokers. The study team will present participants with craving probes while they watch a non-smoking related film. The goal is to examine the ability of this method to capture craving so it can be applied to brain imaging research.

This study aims to explore the perspectives of patients with opioid dependence and health care providers (HCPs) who are involved in the care of individuals with opioid use disorder on how they would feel regarding a contingency management (CM) smartphone game for opioid agonist therapy (OAT). The study team will be obtaining information through focus groups with patients and semi-structured interviews with HCPs.

The purpose of this study is to understand the link between schizophrenia and heat. People with schizophrenia have died at disproportionately high rates in recent heat events. While there is some physiological and biomedical understanding of thermoregulation in people with schizophrenia, understandings of their social vulnerability is lacking. Through interviews with people with schizophrenia, as well as their caregivers and loved ones, the study team aims to get a fuller understanding of their experiences in extreme heat events.

The purpose of this study is to evaluate the efficacy of 25mg of psilocybin versus a placebo in subjects with alcohol use disorder through analysis of the number of heavy drinking days over the eight-week treatment period.

The purpose of this study is to measure patterns of hepatitis C virus (HCV) reinfection after achieving an undetectable viral load at end of treatment on direct-acting aniviral therapy; to determine the threshold of risk reduction practices that protects against HCV reinfection after achieving an undetectable viral load; and to evaluate the potential impact of successful HCV treatment in terms of health care costs and resource utilization.

The purpose of this study is to investigate the effects of cannabis in people using recreational cannabis. This research will examine the cognitive and emotional effects of cannabis oil.

The purpose of this study is to provide real-life evidence for the role of community-based, low-barrier, short-stay facilities in providing care for patients struggling with substance use disorder and severe bacterial infection requiring a prolonged (approximately 2-6 week) course of antibiotics.

The purpose of this study is to assess whether a phone texting service will improve quality of care provided to the patients discharged from the Joseph & Rosalie Segal Family Health Centre at Vancouver General Hospital. Providing additional support, via their mobile phones, and connection to a care navigator, especially after discharge from psychiatric inpatient units may help patients make a seamless transition from hospital to community-based care and can potentially reduce losses to follow-up and unplanned readmissions to hospital.