Centre for Clinical Epidemiology and Evaluation [C2E2]

The Centre for Clinical Epidemiology & Evaluation undertakes research and training and provides evidence-based advice to advance a sustainable health system for British Columbians.

Our focus is on three areas of health research:

  • Clinical research – research that explores the safety, effectiveness and efficiency of health care interventions and procedures (including disease prevention measures);
  • Applied health services and health economics research – research concerned with the organisation, management, financing, delivery and outcomes of care;
  • Knowledge translation – the process of promoting and facilitating evidence-informed decision making at practice, managerial and policy levels.

C2E2 investigators have a diverse range of specialties from family practice and emergency medicine to health economics and outcomes evaluation. They develop research methodology and provide statistical expertise for health care policy makers and VCH health researchers, and provide evidence-based advice to support and advance a sustainable health care system that delivers high quality, safe, and effective care. The the types of questions C2E2 regularly explores are:

  • How does organizational change affect health outcomes?
  • What is the utilization of cardiovascular health care by differing population groups?
  • What is the health and financial burden of asthma to British Columbia?


Dr. Penny Brasher and Dr. Craig Mitton, Centre Co-Directors 


  • Located at Vancouver General Hospital
  • The Centre has 38 affiliated investigators and 13 trainees


Centre for Clinical Epidemiology and Evaluation
Vancouver General Hospital (VGH) - Research Pavilion
828 West 10th Avenue
Vancouver, B.C. V5Z 1L8
Tel: 604.875.4111 x 62187

For more information visit www.c2e2.ca