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  3. Mads Daugaard

Mads Daugaard

Associate Professor
VCH Clinical Title(s)
Molecular Biologist
Research Focus
Cancers
Degrees / Designations

B.Sc., M.Sc., PhD

Contact Info
mads.daugaard@ubc.ca
604-875-4111 x21792
madsdaug1
madsdaugaard

Biography

Dr. Mads Daugaard is a molecular biologist specialized in pre-clinical and translational cancer research. He earned his PhD in 2007 from the Faculty of Health Sciences at the University of Copenhagen for his studies on heat shock proteins in relation to cancer cell survival mechanisms. After completing his PhD, Dr. Daugaard received a junior fellowship award to continue his work at the Danish Cancer Society Research Centre on stress signaling pathways related to DNA damage response mechanisms. In 2010, Dr. Daugaard received a research award from the Danish Cancer Society to do postdoctoral training in molecular pathology at the BC Cancer Research Centre and the Department of Pathology and Laboratory Medicine at the University of British Columbia (UBC).

In 2014, Dr. Daugaard was recruited to the Vancouver Prostate Centre as a senior research scientist and a faculty member of the Department of Urological Sciences at UBC. His ongoing research focuses on molecular and biochemical events underlying sugar-modifications of proteins in solid tumors, chromatin context-dependent DNA repair mechanisms, chemotherapy resistance mechanisms and immune-evasion mechanisms in cancer.

Dr. Daugaard has published original research in top-tier scientific journals and received competitive national and international research funding support from institutions such as the US Department of Defense, the National Cancer Institutes, the Canadian Institutes of Health Research, the Stand Up 2 Cancer initiative, the St. Baldrick’s Foundation and the Vancouver Coastal Health Research Institute. Dr. Daugaard was honoured with the Prostate Cancer Canada Rising Star Award in 2014 and the Robert J. Arceci Innovation Award in 2019. 

Dr. Daugaard is a biotech entrepreneur and a co-founder of the biotech companies VAR2 Pharmaceuticals (2012), VarCT Diagnostics (2017), Rakovina Therapeutics (2020) and SnapCyte Solutions (2022).

News and Awards

Novel discovery slowed prostate cancer growth by targeting its sugar coat

Oct 31, 2022

AI cell analytics app could supercharge biotechnology research

Sep 20, 2022

New molecule could enhance the efficacy of childhood cancer treatments

Jan 8, 2020

Innovation and Translational Research Awards 2019 Recipients

Aug 13, 2019

Award supports research into broad-spectrum childhood cancer treatments

May 21, 2019

People in profile: Maj Sofie Ørum-Madsen

Mar 21, 2019

Malaria leads a new charge against bladder cancer

Apr 20, 2017

Drug created from malaria parasite shows promise as bladder cancer treatment

Apr 20, 2017

Social media helps expand groundbreaking findings on malaria as potential cancer treatment

Oct 23, 2015

Destructive disease shows potential as a cancer treatment

Oct 8, 2015

Publications

  • Cancer discovery -

    Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.

    Zhang HF, Hughes CS, Li W, He JZ, Surdez D, El-Naggar AM, Cheng H, Prudova A, Delaidelli A, Negri GL, Li X, Ørum-Madsen MS, Lizardo MM, Oo HZ, Colborne S, Shyp T, Scopim-Ribeiro R, Hammond CA, Dhez AC, Langman S, Lim JKM, Kung SHY, Li A, Steino A, Daugaard M, Parker SJ, Geltink RIK, Orentas RJ, Xu LY, Morin GB, Delattre O, Dimitrov DS, Sorensen PH
  • Cells -

    A Potential Role for HUWE1 in Modulating Cisplatin Sensitivity.

    Wenmaekers S, Viergever BJ, Kumar G, Kranenburg O, Black PC, Daugaard M, Meijer RP
  • Cell death & disease -

    Development of a bispecific immune engager using a recombinant malaria protein.

    Nordmaj MA, Roberts ME, Sachse ES, Dagil R, Andersen AP, Skeltved N, Grunddal KV, Erdoğan SM, Choudhary S, Gustsavsson T, Ørum-Madsen MS, Moskalev I, Tian W, Yang Z, Clausen TM, Theander TG, Daugaard M, Nielsen MA, Salanti A
  • Oncogene -

    HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.

    Turgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, Hughes CS, Sorensen PH
  • Glycobiology -

    An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer.

    Toledo AG, Pihl J, Spliid CB, Persson A, Nilsson J, Pereira MA, Gustavsson T, Choudhary S, Oo HZ, Black PC, Daugaard M, Esko JD, Larson G, Salanti A, Clausen TM
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