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Sleep

Recruiting

A Pilot Study of Antioxidant Therapy in Obstructive Sleep Apnea Patients

The purpose of this study is to determine if Alpha Lipoic Acid (ALA) reduces inflammation and oxidative stress markers in the blood, as well as 
improved blood vessel function in patients with moderate to severe obstructive sleep apnea (OSA).

Status
Recruiting
Principal Investigator
Rachel Jen
Body Locations and Systems
Lungs and Breathing
Area
Vancouver
Age
35-60

Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart Failure (ADVENT-HF)

Sleep Apnea (SA) is a disorder that causes pauses in breathing during sleep that expose the heart to oxygen deprivation. It is common in patients with heart failure (HF) where it is associated with increased risk of hospitalizations and death. It is not known however whether treating SA reduces these risks. This study is looking at whether a respiratory device known as Adaptive Servo Ventilation (ASV) can reduce the rate of cardiovascular hospitalizations and death in subjects with HF and SA.

Status
Recruiting
Principal Investigator
John Fleetham
Body Locations and Systems
Heart Failure
Sleep Apnea Syndromes
Area
Vancouver
Age
18 and above

Closed for Recruitment

Buying Time: Improving Sleep to Promote Cognitive Function in Older Adults

The purpose of this study is to investigate whether a comprehensive group education combined with a lifestyle "activation" program that includes (a) sleep hygiene course, (b) physical activity promotion, and (c) bright light therapy, can improve both sleep quality and cognitive function among 96 community-dwelling older adults.

 
Status
Closed for Recruitment
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Brain
Area
Vancouver
Age
65-85

Sleep & cognition: Examining the relationship between quality of sleep and cognitive function

We aim to examine the relationship bewteen cognitive function and sleep quality as a function of aging; and to determine whether sleep disruptions differ across individuals with mild cognitivie impairment, depending on stroke-status (i.e., chronic stroke survivors versus non-stroke).  These findings will be used to develop a randomized controlled trial to test interventions designed to improve sleep quality in an effort to promote cognitive function in older adults at risk for dementia.

Status
Closed for Recruitment
Principal Investigator
Teresa Liu-Ambrose
Area
Vancouver
Age
30 and above
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