VCHRI researchers awarded CIHR project grants to support health research

The Canadian Institutes of Health Research (CIHR) has announced the results of its Fall 2021 project grant competition. Congratulations to all the VCHRI researchers who were awarded project grants and priority announcement grants. 

Project Grants

A spatial analysis of inequality in road trauma outcomes in British Columbia
Principal Investigator: Dr. Jeffrey R. Brubacher

Glycocalyx plasticity as an adaptive response to AR pathway-inhibition in prostate cancer
Principal Investigator: Dr. Mads Daugaard

Mixed-methods study investigating the efficacy and acceptance of a seated exercise program delivered virtually to improve mobility in older adults living with stroke
Principal Investigator: Dr. Janice J. Eng
*Conditionally funded at time of posting

A Phase I first-in-human trial of CLIC-2201, a VHH-CD22 CAR-T cell product for the treatment of relapsed/refractory CD22 positive B-cell non-Hodgkin lymphoma
Principal Investigator: Dr. Kevin A. Hay

Light and Ion Maintenance In Treatment of Depression (LIMIT-D) Trial: Feasibility Study
Principal Investigator: Dr. Raymond W. Lam

Moving More: Supporting Uptake of Evidence for Physical Activity in Older Adults with Complex Health Care Needs
Principal Investigators: Dr. Linda C. Li, Dr. Teresa Y. Liu-Ambrose

3-dimensional representation of mouse movement and rapid interaction with cortical brain activity to describe and shape behavior to improve outcome from stroke: insights from real and synthetic data approaches
Principal Investigator: Dr. Timothy H. Murphy

Subject-Specific Biomechanical Modelling in Adult Spinal Deformity Patients: A Surgical Planning and Failure Prediction Toolkit
Principal Investigator: Dr. Thomas R. Oxland

Impact of blood transfusion on cerebral blood flow regulation in experimental and pathological brain hypoxia in humans
Principal Investigator: Dr. Mypinder S. Sekhon

Schizophrenia treatment adherence and driver responsibility for motor vehicle crash
Principal Investigator: Dr. John A. Staples

Metabolic treatment for chronic spinal cord injury in rodents
Principal Investigator: Dr. Wolfram G. Tetzlaff

Using Artificial Intelligence, Big Data and Imaging to Improve Stroke Risk Assessment and Management
Principal Investigator: Dr. Teresa S. Tsang

Optimization and Validation of MCT4-targeting Small Molecule Inhibitors for Treatment of Advanced Cancers
Principal Investigator: Dr. Yuzhuo Wang

Refining the clinical utility of circulating tumour DNA in metastatic bladder cancer
Principal Investigators: Dr. Alexander W. Wyatt, Dr. Bernhard J. Eigl

Read the full list of project grant recipients

Priority Announcement Grants

Gamifying neuro rehabilitation, can we predict who will benefit?
Priority Announcement: Neurosciences, Mental Health and Addiction
Principal Investigator: Dr. Lara Boyd

Novel mechanisms and therapeutic approach for aging-related pruritus
Priority Announcement: Aging
Principal Investigator: Dr. David J. Granville

Lipid Nanoparticle-Mediated Delivery of CRISPR/Cas9 Gene Editing for Neurological Disorders
Priority Announcement: Genetics (Bridge Funding: Research Priorities)
Principal Investigator: Dr. Blair R. Leavitt

Exploring the potential of type-1 regulatory T cells in treatment and recovery from intestinal inflammation in inflammatory bowel disease
Priority Announcement: Infection and Immunity
Principal Investigator: Dr. Theodore S. Steiner

Digital self-tracking for early detection and prevention of endometrial cancer during reproductive aging
Priority Announcement: Equity in Cancer Prevention and Control
Principal Investigator: Dr. Aline Talhouk, Dr. Michael S. Anglesio

Clinical-biomarker predictors of outcome after endometriosis surgery
Priority Announcement: Patient-Oriented Research
Principal Investigators: Dr. Paul Yong, Dr. Aline Talhouk, Dr. Michael S. Anglesio

Read the full list of priority announcement grant recipients