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Healthy Volunteers

Whether you are healthy or have a medical condition, there are opportunities to participate in a research study. Health research ranges from simple questionnaires or screening tests, to clinical trials of a new drug or device.

Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants

The purpose of this study is evaluate the safety and efficacy of a new vaccine to protect children against bacteria that can lead to pneumococcal disease. 

Status
Recruiting
Principal Investigator
Manish Sadarangani
Body Locations and Systems
Immunizations
Area
Vancouver
Age
2 months

Lung health benefits of e-cigarette cessation

The purpose of this study is to determine the lung and immune function benefits of stopping vaping for 72 hours in young adults who use e-cigarettes containing nicotine. The study also aims to determine if telling participants of their own personalized changes to their lung and immune function following the 72 hour abstinence period affects their motivation in quitting vaping.

Status
Recruiting
Principal Investigator
Christopher Carlsten
Body Locations and Systems
Smoking Cessation
Area
Vancouver
Age
19 - 35

Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT)

The purpose of this study is to assess the effects of the COVID-19 outbreak and related quarantine measures on the physical and mental well-being of health care workers, as well as the general population.

 

Status
Recruiting
Principal Investigator
Lakshmi Yatham
Area
Vancouver
Age
6 and above

Osteoarthritis Running & Cartilage Assessment (ORCA)

The purpose of this study is to examine the safety of running for knee joint health through an assessment of running biomechanics and MRI-derived measures of cartilage composition. 

Status
Recruiting
Principal Investigator
Michael Hunt
Body Locations and Systems
Osteoarthritis
Area
Vancouver
Age
40 years and above

Online study: Diversity of sexual preferences

We would like to explore different aspects of sexual identity among individuals who self-identify as asexual, bisexual, gay or heterosexual.

Recruitment Poster

Status
Recruiting
Principal Investigator
Lori Brotto
Body Locations and Systems
Men's and Women's Health
Sexual Health
Area
Vancouver
Age
19-45 years

Birth, childhood health and psychosis outcomes

The goal of the current study is to determine the prevalence, rate, and types of pregnancy complications and early life events that may be associated with the emergence of psychosis and related metabolic disorder in patients with schizophrenia spectrum disorders.

Recruitment Poster

Status
Recruiting
Principal Investigator
Donna Jane M Lang
Body Locations and Systems
Men's and Women's Health
Area
Vancouver
Age
16-45

Improving Hearing Assessment in Newborns

To determine how much noise is required during testing to make sure that each ear is assessed separately during an auditory assessment in infants. 

Status
Recruiting
Principal Investigator
Susan Small
Body Locations and Systems
Hearing Disorders and Deafness
Area
Vancouver
Age
18 months old or younger

Correlation Between PET and Advanced MRI in Multiple Sclerosis

This is an observational study designed to determine the relationship between quantitative advanced MRI measures and OCT with PET measurements of microglial activation and myelin health. 

Status
Recruiting
Principal Investigator
Robert Carruthers
Body Locations and Systems
Multiple Sclerosis
Area
Vancouver
Age
18-60

AMPLATZER™ LAA Occluder Post Approval Study (PAS)

The AMPLATZER LAA Occluder is a transcatheter, self-expanding nitinol device intended for use in preventing thrombus embolization from the LAA. The purpose of this study is to compile real world outcome data on the use of AMPLATZER LAA Occluder in subjects with non-valvular atrial fibrillation (NVAF)

Status
Recruiting
Principal Investigator
Jacqueline Saw
Body Locations and Systems
Atrial Fibrillation
Stroke
Area
Vancouver
Age
18 and above

Brain Health and Exercise in Schizophrenia (PEHP)

To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers. Psychosis patients often suffer from a number of cognitive difficulties, including poor memory function, poor problem-solving capacity and difficulties with attention and concentration. These problems are not well addressed by current clinical treatments.

Status
Recruiting
Principal Investigator
Donna Jane M Lang
Body Locations and Systems
Brain
Area
Vancouver
Age
16-45

International Lung Screen Trial (ILST)

People who may be at increased risk of lung cancer due to age and smoking history will be invited to participate in this international study to determine the best way of using computed tomography (CT) of the chest to screen for early lung cancer. Overseas data show that CT screening (screening tests can find diseases early, when they're easier to treat) can reduce deaths from lung cancer and this study will help determine who is most likely benefit from screening.

Status
Recruiting
Principal Investigator
Stephen Lam
Body Locations and Systems
Lung Cancer
Area
Vancouver
Age
55-80

Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer (LS2)

This study will maximize identification of women with Lynch Syndrome using an enhanced screening strategy to identify those at risk. These women will be referred to genetic counselling for testing and those found to have Lynch Syndrome will be asked to invite first degree relatives to participate and undergo genetic testing for Lynch Syndrome.

Status
Recruiting
Principal Investigator
Janice Kwon
Body Locations and Systems
Ovarian Disorders
Area
Vancouver
Age
18-70

Examining decision making in Parkinson's Disease

The purpose of this study is to examine the effects of Parkinson's medication on decision making and risk taking in healthy control participants. 

Status
Recruiting
Principal Investigator
Jason Barton
Body Locations and Systems
Parkinson's Disease
Area
Vancouver
Age
50 and above

MINT-01 (A Medium Chain Triglyceride INTervention for Alzheimer Disease (A MINT for AD Study)

This study will test the safety and tolerability of a medium chain triglyceride (MCT) supplement in those with Alzheimer Disease (AD). 

Recruitment Poster

Status
Recruiting
Principal Investigator
Haakon Nygaard
Body Locations and Systems
Alzheimer's Disease
Area
Vancouver
Age
50-90

From Clinic to Community Study (C2C)

This study is a 12-month study. There are two different groups in the study. Both groups will enter the study after the graduation from 8-hour diabetes education course taught at VGH, St. Paul's, or Richmond Hospital. The first group will receive on-going support from their peers who have diabetes and are trained specifically to help other patients with diabetes. The second group will receive the usual care.

Status
Recruiting
Principal Investigator
Tricia Tang
Body Locations and Systems
Diabetes - Type 2
Area
Vancouver
Age
21 and above

Once Daily Dosing to Improve Medication Adherence and Patient Satisfaction in Kidney Transplant Recipients (OnceDaily)

Patient failure to take medications as prescribed (medication non-adherence) is now identified as an important cause of kidney transplant failure. The availability of new drugs that are taken once daily may improve patient adherence compared to older drugs that had to be taken twice per day. In this study, patients will be converted to a medication schedule where all medications are taken once daily with the goal of improving patient adherence and satisfaction.

Status
Recruiting
Principal Investigator
John Gill
Body Locations and Systems
Kidney Transplantation
Area
Vancouver
Age
18 and above

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

The purpose of this study is to assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have, or are at risk of having an Alzheimer's disease-causing mutation by determining if treatment with the study drug slows the rate of progression of cognitive impairment and improves disease-related biomarkers.
This study also offers an observational component collecting cognitive assessment data until the availability of an enrolling drug treatment group, referred to as cognitive run-in (CRI).

 

Status
Recruiting
Principal Investigator
Ging-Yuek Robin Hsiung
Body Locations and Systems
Alzheimer's Disease
Neurologic Diseases
Dementia
Area
Vancouver
Age
18-80

Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Children With ADHD

This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or inattentive-type (ADHD-IA) and currently on > 20 mg/day of psychostimulants (psychostimulants) on: a) their current dose of psychostimulants, vs. b) a lower-dose of psychostimulants (half of their current dose).

Status
Recruiting
Principal Investigator
Adele Diamond
Body Locations and Systems
Brain
Area
Vancouver
Age
6-18

A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])

Percutaneous nephrolithotomy (PCNL) is a surgical procedure that is standard of care for the removal of large kidney stones. PCNL involves removal of the stone(s) from the kidney through a temporary tract that is percutaneously placed through the patient's back during surgery. There is a significant risk of urinary tract infection after PCNL but wide clinical variation in use of prophylactic antibiotics in the days leading up to surgery.

Status
Recruiting
Principal Investigator
Ben Chew
Body Locations and Systems
Kidney Stones
Urinary Tract Infections
Area
Vancouver
Age
18 and above

Urine and Stool Analysis in Kidney Stone Disease

The purpose of this study is to add to the investigators' quest to understanding stone disease, by evaluating the metabolites excretion in urine and its relation to microflora present in the stool.

Status
Recruiting
Principal Investigator
Ben Chew
Body Locations and Systems
Kidney Stones
Area
Vancouver
Age
19-90

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