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Healthy Volunteers

Whether you are healthy or have a medical condition, there are opportunities to participate in a research study. Health research ranges from simple questionnaires or screening tests, to clinical trials of a new drug or device.

Validating markers for Alzheimer's disease

The purpose of this study is to collect brain scans, blood samples, memory test scores and cerebrospinal fluid from people with Alzheimer's disease (AD), mild cognitive impairment or no memory impairment. The information collected in the study may help characterize the early stages of AD, and shape the criteria for earlier diagnosis and treatment of AD. It will also be used to discover, standardize and validate measures and biomarkers that are used in AD research. The ADNI4 study is a continuation of the ADNI3 study and will also open to enroll new participants.

Status
Recruiting
Principal Investigator
Ging-Yuek Robin Hsiung
Body Locations and Systems
Brain and Nerves
Alzheimer's Disease
Dementia
Age
55-90

Improving our understanding of functioning in psychosis

The purpose of this study is to contribute to improving our understanding of functioning in psychosis. Memory is an important predictor of how well individuals affected by schizophrenia and related psychoses are able function in their social and occupational lives. However, the exact structures and functions in the brain responsible for this relationship are currently unknown.

Status
Recruiting
Principal Investigator
Todd Woodward
Body Locations and Systems
Brain and Nerves
Age
18-60

Collecting data for the Pacific Parkinson’s Research Centre Biobank

The purpose of this study is to collect biospecimens (fecal, urine, blood) and clinical data to serve as a resource for future research on Parkinson’s disease and other movement disorders. The careful collection, storage and retrieval of biospecimens and medical information for research projects are critical for improving understanding of healthy development and disease mechanisms and the subsequent development of effective treatments. Biospecimens from this biobank will be made available for ethically-approved studies.

Status
Recruiting
Principal Investigator
Silke Appel-Cresswell
Body Locations and Systems
Blood, Heart and Circulation
Brain and Nerves
Parkinson's Disease
Digestive System
Immune System
Kidneys and Urinary System
Mouth and Teeth
Age
19 and above

Investigating endometriosis and brown adipose tissue activity

The purpose of this study is to compare brown adipose tissue (BAT) activity in women/people diagnosed with endometriosis to similar healthy controls. BAT activity is measured twice in a random order during the early part of the menstrual cycle (follicular phase) and following egg release/ovulation (luteal phase). The study team will investigate whether BAT activity in women with endometriosis differs from healthy control women who are of similar age and body mass index.

Status
Recruiting
Principal Investigator
Jerilynn C. Prior
Body Locations and Systems
Endocrine System
Endometriosis
Sexual Health
Age
19-35

Supporting physical activity for mobility-limited older adults

The purpose of this study is to determine if a 26-week health coaching program can increase time spent in moderate to vigorous physical activity and improve mobility compared with a 26-week group health education program in older adults with limited mobility.

Status
Recruiting
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Brain and Nerves
Age
70-89

Studying the safety of Montbretin A for diabetes

The purpose of this study is to investigate the safety and tolerability of Montbretin A, a new natural health product made from garden flower, in treating healthy individuals or individuals with type 2 diabetes by reducing hyperglycemia episodes.

Status
Recruiting
Principal Investigator
Robert Petrella
Age
19-65

Predicting treatment outcomes for major depression

The purpose of this study is to test whether a specific combination of biomarkers discovered during previous studies can help predict how someone experiencing a major depressive episode will respond to treatment. The study will also explore other possible biomarkers that may predict treatment response, which may help in the future development of tests that can guide treatment choice more effectively and more quickly.

Status
Recruiting
Principal Investigator
Raymond Lam
Body Locations and Systems
Brain and Nerves
Age
18-60

Exploring the use of 3D printers in rehabilitation

The purpose of this study is to investigate prosthetists' and occupational therapists' perceptions of 3D printing and explore their perspectives on the potential application of this technology in clinical settings through interviews.

Status
Recruiting
Principal Investigator
Ben Mortenson

Understanding the link between schizophrenia, schizoaffective disorder and heat

The purpose of this study is to understand the link between schizophrenia and heat. People with schizophrenia have died at disproportionately high rates in recent heat events. While there is some physiological and biomedical understanding of thermoregulation in people with schizophrenia, understandings of their social vulnerability is lacking. Through interviews with people with schizophrenia, as well as their caregivers and loved ones, the study team aims to get a fuller understanding of their experiences in extreme heat events.

Status
Recruiting
Principal Investigator
Liv Yoon

Examining the cognitive effects of cannabis on stress response

The purpose of this study is to investigate the effects of cannabis in people using recreational cannabis. This research will examine the cognitive and emotional effects of cannabis oil.

Status
Recruiting
Principal Investigator
Christian Schütz
Body Locations and Systems
Brain and Nerves
Age
19-35

Reshaping the path of mild cognitive impairment with exercise training

The purpose of the study is to investigate the effects of different types of exercise training on cognitive function. Investigators aim to assess the individual effects of aerobic and resistance training, as well as the interaction effect of combining the two types of exercise training, on cognitive function in older adults with mild cognitive impairment.

Status
Recruiting
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Brain and Nerves
Age
65-85

Using eye movements to understand cognitive and motor functions in Parkinson’s Disease

The purpose of this study is to test visual abilities and eye movements in patients with Parkinson's disease and healthy control participants and to link dysfunctions to cognitive abilities and disease severity.

Recruitment Poster

Status
Recruiting
Principal Investigator
Miriam Spering
Body Locations and Systems
Brain and Nerves
Eyes and Vision
Age
50-85

Neurocardiac predictors of treatment response to rTMS in depression

The purpose of this study is to explore whether heart rate variability (HRV) normalization may serve as a surrogate marker of the changes in brain function caused by repetitive transcranial magnetic stimulation (rTMS) that are associated with symptomatic improvement in depression.

Status
Recruiting
Principal Investigator
Fidel Vila-Rodriguez
Body Locations and Systems
Brain and Nerves
Age
19-65

Asian Cohort for Alzheimer’s Disease

The purpose of this study is to investigate the impact of genetic and non-genetic risk factors for Alzheimer’s disease (AD), evaluate differential
effects of sex on AD risk, and predict diagnosis of AD using dementia risk scores derived from genetic and nongenetic risk factors.

Status
Recruiting
Principal Investigator
Ging-Yuek Robin Hsiung
Body Locations and Systems
Brain
Alzheimer's Disease
Age
60 and above

Effects of Sex on Belt Fit in Relation to Skeletal Geometry

The purpose of this study is to determine if there are sex differences in seatbelt fit by quantifying male and female volunteers’ seatbelt fits relative to external body geometry and skeletal posture using an upright MRI. 

Status
Recruiting
Principal Investigator
Peter Cripton
Area
Vancouver
Age
19-60

Understanding perimenopausal brain health

The purpose of this study is to is to examine the effects of 12 weeks of high-intensity interval training on the cognitive health of perimenopausal women.

Status
Recruiting
Principal Investigator
Teresa Liu-Ambrose
Body Locations and Systems
Brain and Nerves
Brain
Women's Health
Menopause
Area
Vancouver
Age
40-55

Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants

The purpose of this study is evaluate the safety and efficacy of a new vaccine to protect children against bacteria that can lead to pneumococcal disease. 

Status
Recruiting
Principal Investigator
Manish Sadarangani
Body Locations and Systems
Immunizations
Area
Vancouver
Age
2 months

Lung health benefits of e-cigarette cessation

The purpose of this study is to determine the lung and immune function benefits of stopping vaping for 72 hours in young adults who use e-cigarettes containing nicotine. The study also aims to determine if telling participants of their own personalized changes to their lung and immune function following the 72 hour abstinence period affects their motivation in quitting vaping.

Status
Recruiting
Principal Investigator
Christopher Carlsten
Body Locations and Systems
Smoking Cessation
Area
Vancouver
Age
19 - 35

Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT)

The purpose of this study is to assess the effects of the COVID-19 outbreak and related quarantine measures on the physical and mental well-being of health care workers, as well as the general population.

 

Status
Recruiting
Principal Investigator
Lakshmi Yatham
Area
Vancouver
Age
6 and above

Osteoarthritis Running & Cartilage Assessment (ORCA)

The purpose of this study is to examine the safety of running for knee joint health through an assessment of running biomechanics and MRI-derived measures of cartilage composition. 

Status
Recruiting
Principal Investigator
Michael Hunt
Body Locations and Systems
Osteoarthritis
Area
Vancouver
Age
40 years and above

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