The purpose of this study is to investigate the effects of cannabis in people who use recreational cannabis and meet criteria for heavy drinking. Investigators will examine the emotional and cognitive effects of cannabis oil on social and cognitive functioning.
Whether you are healthy or have a medical condition, there are opportunities to participate in a research study. Health research ranges from simple questionnaires or screening tests, to clinical trials of a new drug or device.
The purpose of the study is to investigate the effects of different types of exercise training on cognitive function. Investigators aim to assess the individual effects of aerobic and resistance training, as well as the interaction effect of combining the two types of exercise training, on cognitive function in older adults with mild cognitive impairment.
The purpose of this study is to test visual abilities and eye movements in patients with Parkinson's disease and healthy control participants and to link dysfunctions to cognitive abilities and disease severity.
The purpose of this study is to explore whether heart rate variability (HRV) normalization may serve as a surrogate marker of the changes in brain function caused by repetitive transcranial magnetic stimulation (rTMS) that are associated with symptomatic improvement in depression.
The purpose of this study is to investigate changes in the brain in people affected by Parkinson’s disease using PET and fMRI imaging.
The purpose of this study is to investigate the impact of genetic and non-genetic risk factors for Alzheimer’s disease (AD), evaluate differential
effects of sex on AD risk, and predict diagnosis of AD using dementia risk scores derived from genetic and nongenetic risk factors.
The purpose of this study is to determine if there are sex differences in seatbelt fit by quantifying male and female volunteers’ seatbelt fits relative to external body geometry and skeletal posture using an upright MRI.
The purpose of this study is to is to examine the effects of 12 weeks of high intensity interval training on the cognitive health of perimenopausal woman.
Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants
The purpose of this study is evaluate the safety and efficacy of a new vaccine to protect children against bacteria that can lead to pneumococcal disease.
The purpose of this study is to determine the lung and immune function benefits of stopping vaping for 72 hours in young adults who use e-cigarettes containing nicotine. The study also aims to determine if telling participants of their own personalized changes to their lung and immune function following the 72 hour abstinence period affects their motivation in quitting vaping.
The purpose of this study is to assess the effects of the COVID-19 outbreak and related quarantine measures on the physical and mental well-being of health care workers, as well as the general population.
The purpose of this study is to examine the safety of running for knee joint health through an assessment of running biomechanics and MRI-derived measures of cartilage composition.
The goal of the current study is to determine the prevalence, rate, and types of pregnancy complications and early life events that may be associated with the emergence of psychosis and related metabolic disorder in patients with schizophrenia spectrum disorders.
To determine how much noise is required during testing to make sure that each ear is assessed separately during an auditory assessment in infants.
This is an observational study designed to determine the relationship between quantitative advanced MRI measures and OCT with PET measurements of microglial activation and myelin health.
The AMPLATZER LAA Occluder is a transcatheter, self-expanding nitinol device intended for use in preventing thrombus embolization from the LAA. The purpose of this study is to compile real world outcome data on the use of AMPLATZER LAA Occluder in subjects with non-valvular atrial fibrillation (NVAF)
To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers. Psychosis patients often suffer from a number of cognitive difficulties, including poor memory function, poor problem-solving capacity and difficulties with attention and concentration. These problems are not well addressed by current clinical treatments.
People who may be at increased risk of lung cancer due to age and smoking history will be invited to participate in this international study to determine the best way of using computed tomography (CT) of the chest to screen for early lung cancer. Overseas data show that CT screening (screening tests can find diseases early, when they're easier to treat) can reduce deaths from lung cancer and this study will help determine who is most likely benefit from screening.
Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer (LS2)
This study will maximize identification of women with Lynch Syndrome using an enhanced screening strategy to identify those at risk. These women will be referred to genetic counselling for testing and those found to have Lynch Syndrome will be asked to invite first degree relatives to participate and undergo genetic testing for Lynch Syndrome.